2lf1: Difference between revisions

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-[[Image:2lf1.png|left|200px]]
-{{STRUCTURE_2lf1|  PDB=2lf1  |  SCENE=  }}
+==Solution structure of L. casei dihydrofolate reductase complexed with NADPH, 30 structures==
+<StructureSection load='2lf1' size='340' side='right'caption='[[2lf1]]' scene=''>
-===Solution structure of L. casei dihydrofolate reductase complexed with NADPH, 30 structures===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[2lf1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lacticaseibacillus_casei Lacticaseibacillus casei]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LF1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LF1 FirstGlance]. <br>
-{{ABSTRACT_PUBMED_21410224}}
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr>
-==About this Structure==
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lf1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lf1 OCA], [https://pdbe.org/2lf1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lf1 RCSB], [https://www.ebi.ac.uk/pdbsum/2lf1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lf1 ProSAT]</span></td></tr>
-[[2lf1]] is a 1 chain structure of [[Dihydrofolate reductase]] with sequence from [http://en.wikipedia.org/wiki/Lactobacillus_casei Lactobacillus casei]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LF1 OCA].
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/DYR_LACCA DYR_LACCA] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
 ==See Also==
-*[[Dihydrofolate reductase|Dihydrofolate reductase]]
+*[[Dihydrofolate reductase 3D structures|Dihydrofolate reductase 3D structures]]
+__TOC__
-==Reference==
+</StructureSection>
-<ref group="xtra">PMID:021410224</ref><references group="xtra"/>
+[[Category: Lacticaseibacillus casei]]
-[[Category: Dihydrofolate reductase]]
+[[Category: Large Structures]]
-[[Category: Lactobacillus casei]]
+[[Category: Birdsall B]]
-[[Category: Birdsall, B.]]
+[[Category: Feeney J]]
-[[Category: Feeney, J.]]
+[[Category: Kovalevskaya N]]
-[[Category: Kovalevskaya, N.]]
+[[Category: Polshakov V]]
-[[Category: Polshakov, V.]]
-[[Category: Dhfr]]
-[[Category: Oxidoreductase]]
-[[Category: Positive cooperativity]]
-[[Category: Protein-ligand interaction]]