2l5u: Difference between revisions

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[[Image:2l5u.png|left|200px]]


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==Structure of the first PHD finger (PHD1) from CHD4 (Mi2b)==
The line below this paragraph, containing "STRUCTURE_2l5u", creates the "Structure Box" on the page.
<StructureSection load='2l5u' size='340' side='right'caption='[[2l5u]]' scene=''>
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== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2l5u]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2L5U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2L5U FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
{{STRUCTURE_2l5u|  PDB=2l5u  |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2l5u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2l5u OCA], [https://pdbe.org/2l5u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2l5u RCSB], [https://www.ebi.ac.uk/pdbsum/2l5u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2l5u ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CHD4_HUMAN CHD4_HUMAN] Component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin by deacetylating histones.<ref>PMID:9804427</ref> <ref>PMID:17626165</ref>


===Structure of the first PHD finger (PHD1) from CHD4 (Mi2b)===
==See Also==
 
*[[Chromodomain-helicase-DNA-binding protein 3D structures|Chromodomain-helicase-DNA-binding protein 3D structures]]
 
*[[Helicase 3D structures|Helicase 3D structures]]
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== References ==
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<references/>
(as it appears on PubMed at http://www.pubmed.gov), where 21278251 is the PubMed ID number.
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</StructureSection>
{{ABSTRACT_PUBMED_21278251}}
 
==About this Structure==
[[2l5u]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2L5U OCA].
 
==Reference==
<ref group="xtra">PMID:21278251</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Kwan, A H.]]
[[Category: Large Structures]]
[[Category: Mackay, J P.]]
[[Category: Kwan AH]]
[[Category: Mansfield, R E.]]
[[Category: Mackay JP]]
[[Category: Mansfield RE]]

Latest revision as of 09:53, 1 May 2024

Structure of the first PHD finger (PHD1) from CHD4 (Mi2b)Structure of the first PHD finger (PHD1) from CHD4 (Mi2b)

Structural highlights

2l5u is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Solution NMR
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

CHD4_HUMAN Component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin by deacetylating histones.[1] [2]

See Also

References

  1. ↑ Tong JK, Hassig CA, Schnitzler GR, Kingston RE, Schreiber SL. Chromatin deacetylation by an ATP-dependent nucleosome remodelling complex. Nature. 1998 Oct 29;395(6705):917-21. PMID:9804427 doi:http://dx.doi.org/10.1038/27699
  2. ↑ Sillibourne JE, Delaval B, Redick S, Sinha M, Doxsey SJ. Chromatin remodeling proteins interact with pericentrin to regulate centrosome integrity. Mol Biol Cell. 2007 Sep;18(9):3667-80. Epub 2007 Jul 11. PMID:17626165 doi:http://dx.doi.org/10.1091/mbc.E06-07-0604
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