2kx7: Difference between revisions

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'''Unreleased structure'''


The entry 2kx7 is ON HOLD  until Paper Publication
==Solution structure of the E.coli RcsD-ABL domain (residues 688-795)==
 
<StructureSection load='2kx7' size='340' side='right'caption='[[2kx7]]' scene=''>
Authors: Rogov, V.V., Schmoee, K., Rogova, N.Y., Loehr, F., Bernhard, F., Doetsch, V.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2kx7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KX7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KX7 FirstGlance]. <br>
Description: Solution structure of the E.coli RcsD-ABL domain (residues 688-795)
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kx7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kx7 OCA], [https://pdbe.org/2kx7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kx7 RCSB], [https://www.ebi.ac.uk/pdbsum/2kx7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kx7 ProSAT]</span></td></tr>
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 26 08:12:53 2010''
</table>
== Function ==
[https://www.uniprot.org/uniprot/RCSD_ECOLI RCSD_ECOLI] Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB. The system controls expression of genes involved in colanic acid capsule synthesis, biofilm formation and cell division.[HAMAP-Rule:MF_00980]<ref>PMID:10564486</ref> <ref>PMID:11309126</ref> <ref>PMID:11758943</ref> <ref>PMID:13129944</ref> <ref>PMID:14651646</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Escherichia coli K-12]]
[[Category: Large Structures]]
[[Category: Bernhard F]]
[[Category: Doetsch V]]
[[Category: Loehr F]]
[[Category: Rogov VV]]
[[Category: Rogova NY]]
[[Category: Schmoee K]]

Latest revision as of 09:49, 1 May 2024

Solution structure of the E.coli RcsD-ABL domain (residues 688-795)Solution structure of the E.coli RcsD-ABL domain (residues 688-795)

Structural highlights

2kx7 is a 1 chain structure with sequence from Escherichia coli K-12. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Solution NMR
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

RCSD_ECOLI Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB. The system controls expression of genes involved in colanic acid capsule synthesis, biofilm formation and cell division.[HAMAP-Rule:MF_00980][1] [2] [3] [4] [5]

References

  1. ↑ Carballes F, Bertrand C, Bouche JP, Cam K. Regulation of Escherichia coli cell division genes ftsA and ftsZ by the two-component system rcsC-rcsB. Mol Microbiol. 1999 Nov;34(3):442-50. PMID:10564486
  2. ↑ Takeda S, Fujisawa Y, Matsubara M, Aiba H, Mizuno T. A novel feature of the multistep phosphorelay in Escherichia coli: a revised model of the RcsC --> YojN --> RcsB signalling pathway implicated in capsular synthesis and swarming behaviour. Mol Microbiol. 2001 Apr;40(2):440-50. PMID:11309126
  3. ↑ Chen MH, Takeda S, Yamada H, Ishii Y, Yamashino T, Mizuno T. Characterization of the RcsC-->YojN-->RcsB phosphorelay signaling pathway involved in capsular synthesis in Escherichia coli. Biosci Biotechnol Biochem. 2001 Oct;65(10):2364-7. PMID:11758943
  4. ↑ Hagiwara D, Sugiura M, Oshima T, Mori H, Aiba H, Yamashino T, Mizuno T. Genome-wide analyses revealing a signaling network of the RcsC-YojN-RcsB phosphorelay system in Escherichia coli. J Bacteriol. 2003 Oct;185(19):5735-46. PMID:13129944
  5. ↑ Ferrieres L, Clarke DJ. The RcsC sensor kinase is required for normal biofilm formation in Escherichia coli K-12 and controls the expression of a regulon in response to growth on a solid surface. Mol Microbiol. 2003 Dec;50(5):1665-82. PMID:14651646
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