2k2o: Difference between revisions

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-[[Image:2k2o.png|left|200px]]
-{{STRUCTURE_2k2o|  PDB=2k2o  |  SCENE=  }}
+==Solution Structure of the inner DysF domain of human myoferlin==
+<StructureSection load='2k2o' size='340' side='right'caption='[[2k2o]]' scene=''>
-===Solution Structure of the inner DysF domain of human myoferlin===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[2k2o]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K2O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2K2O FirstGlance]. <br>
-{{ABSTRACT_PUBMED_18495154}}
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2k2o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k2o OCA], [https://pdbe.org/2k2o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2k2o RCSB], [https://www.ebi.ac.uk/pdbsum/2k2o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2k2o ProSAT]</span></td></tr>
-==About this Structure==
+</table>
-[[2k2o]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K2O OCA].
+== Function ==
+[https://www.uniprot.org/uniprot/MYOF_HUMAN MYOF_HUMAN] Calcium/phospholipid-binding protein that plays a role in the plasmalemma repair mechanism of endothelial cells that permits rapid resealing of membranes disrupted by mechanical stress. Involved in endocytic recycling. Implicated in VEGF signal transduction by regulating the levels of the receptor KDR (By similarity).
-==Reference==
+== Evolutionary Conservation ==
-<ref group="xtra">PMID:018495154</ref><references group="xtra"/>
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k2/2k2o_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2k2o ConSurf].
+<div style="clear:both"></div>
+__TOC__
+</StructureSection>
 [[Category: Homo sapiens]]
-[[Category: Driscoll, P.]]
+[[Category: Large Structures]]
-[[Category: Harris, R.]]
+[[Category: Driscoll P]]
-[[Category: Keep, N.]]
+[[Category: Harris R]]
-[[Category: Patel, P.]]
+[[Category: Keep N]]
-[[Category: Dysf]]
+[[Category: Patel P]]
-[[Category: Dysferlin]]
-[[Category: Limb-girdle]]
-[[Category: Membrane]]
-[[Category: Membrane protein]]
-[[Category: Muscular dystrophy]]
-[[Category: Myoferlin]]
-[[Category: Nucleus]]
-[[Category: Phosphoprotein]]
-[[Category: Transmembrane]]