1x95: Difference between revisions

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[[Image:1x95.png|left|200px]]


{{STRUCTURE_1x95|  PDB=1x95  |  SCENE=  }}
==Solution structure of the DNA-hexamer ATGCAT complexed with DNA Bis-intercalating Anticancer Drug XR5944 (MLN944)==
 
<StructureSection load='1x95' size='340' side='right'caption='[[1x95]]' scene=''>
===solution structure of the B-DNA hexamer ATGCAT complexed with MLN944, a bisphenazine anticancer drug===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1x95]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X95 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1X95 FirstGlance]. <br>
{{ABSTRACT_PUBMED_15317822}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=XR2:1-METHYL-9-[12-(9-METHYLPHENAZIN-10-IUM-1-YL)-12-OXO-2,11-DIAZA-5,8-DIAZONIADODEC-1-ANOYL]PHENAZIN-10-IUM'>XR2</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1x95 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1x95 OCA], [https://pdbe.org/1x95 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1x95 RCSB], [https://www.ebi.ac.uk/pdbsum/1x95 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1x95 ProSAT]</span></td></tr>
[[1x95]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X95 OCA].  
</table>
[[Category: Dai, J.]]
__TOC__
[[Category: Mistry, P.]]
</StructureSection>
[[Category: Ooi, A T.]]
[[Category: Large Structures]]
[[Category: Punchihewa, C.]]
[[Category: Dai J]]
[[Category: Yang, D.]]
[[Category: Mistry P]]
[[Category: Anticancer drug]]
[[Category: Ooi AT]]
[[Category: Ap-1]]
[[Category: Punchihewa C]]
[[Category: Dna]]
[[Category: Yang D]]
[[Category: Mln944]]
[[Category: Novel dna binding]]
[[Category: Transcription inhibition]]

Latest revision as of 09:36, 1 May 2024

Solution structure of the DNA-hexamer ATGCAT complexed with DNA Bis-intercalating Anticancer Drug XR5944 (MLN944)Solution structure of the DNA-hexamer ATGCAT complexed with DNA Bis-intercalating Anticancer Drug XR5944 (MLN944)

Structural highlights

1x95 is a 2 chain structure. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Solution NMR
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT
Drag the structure with the mouse to rotate

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OCA
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