1s6l: Difference between revisions

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{{Seed}}
[[Image:1s6l.png|left|200px]]


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==Solution structure of MerB, the Organomercurial Lyase involved in the bacterial mercury resistance system==
The line below this paragraph, containing "STRUCTURE_1s6l", creates the "Structure Box" on the page.
<StructureSection load='1s6l' size='340' side='right'caption='[[1s6l]]' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1s6l]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S6L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1S6L FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1s6l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1s6l OCA], [https://pdbe.org/1s6l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1s6l RCSB], [https://www.ebi.ac.uk/pdbsum/1s6l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1s6l ProSAT]</span></td></tr>
{{STRUCTURE_1s6l|  PDB=1s6l  |  SCENE=  }}
</table>
 
== Function ==
===Solution structure of MerB, the Organomercurial Lyase involved in the bacterial mercury resistance system===
[https://www.uniprot.org/uniprot/MERB_ECOLX MERB_ECOLX] Cleaves the carbon-mercury bond of organomercurials such as phenylmercuric acetate. One product is Hg(2+), which is subsequently detoxified by the mercuric reductase (By similarity).
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/s6/1s6l_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_15222745}}
    <text>to colour the structure by Evolutionary Conservation</text>
 
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==About this Structure==
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1s6l ConSurf].
1S6L is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S6L OCA].  
<div style="clear:both"></div>
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:15222745</ref><ref group="xtra">PMID:15213467</ref><references group="xtra"/>
[[Category: Alkylmercury lyase]]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Benison, G C.]]
[[Category: Large Structures]]
[[Category: Legault, P.]]
[[Category: Benison GC]]
[[Category: Lello, P Di.]]
[[Category: Di Lello P]]
[[Category: Omichinski, J G.]]
[[Category: Legault P]]
[[Category: Pitts, K E.]]
[[Category: Omichinski JG]]
[[Category: Summers, A O.]]
[[Category: Pitts KE]]
[[Category: Valafar, H.]]
[[Category: Summers AO]]
[[Category: Lyase]]
[[Category: Valafar H]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 08:15:14 2009''

Latest revision as of 09:34, 1 May 2024

Solution structure of MerB, the Organomercurial Lyase involved in the bacterial mercury resistance systemSolution structure of MerB, the Organomercurial Lyase involved in the bacterial mercury resistance system

Structural highlights

1s6l is a 1 chain structure with sequence from Escherichia coli. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Solution NMR
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

MERB_ECOLX Cleaves the carbon-mercury bond of organomercurials such as phenylmercuric acetate. One product is Hg(2+), which is subsequently detoxified by the mercuric reductase (By similarity).

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
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