1qal: Difference between revisions

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-{{Seed}}
-[[Image:1qal.png|left|200px]]
-<!--
+==THE ACTIVE SITE BASE CONTROLS COFACTOR REACTIVITY IN ESCHERICHIA COLI AMINE OXIDASE : X-RAY CRYSTALLOGRAPHIC STUDIES WITH MUTATIONAL VARIANTS==
-The line below this paragraph, containing "STRUCTURE_1qal", creates the "Structure Box" on the page.
+<StructureSection load='1qal' size='340' side='right'caption='[[1qal]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1qal]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QAL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QAL FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=TPQ:5-(2-CARBOXY-2-AMINOETHYL)-2-HYDROXY-1,4-BENZOQUINONE'>TPQ</scene></td></tr>
-{{STRUCTURE_1qal|  PDB=1qal  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qal FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qal OCA], [https://pdbe.org/1qal PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qal RCSB], [https://www.ebi.ac.uk/pdbsum/1qal PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qal ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/AMO_ECOLI AMO_ECOLI] The enzyme prefers aromatic over aliphatic amines.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qa/1qal_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1qal ConSurf].
+<div style="clear:both"></div>
-===THE ACTIVE SITE BASE CONTROLS COFACTOR REACTIVITY IN ESCHERICHIA COLI AMINE OXIDASE : X-RAY CRYSTALLOGRAPHIC STUDIES WITH MUTATIONAL VARIANTS===
+==See Also==
+*[[Copper amine oxidase 3D structures|Copper amine oxidase 3D structures]]
+__TOC__
-<!--
+</StructureSection>
-The line below this paragraph, {{ABSTRACT_PUBMED_10387067}}, adds the Publication Abstract to the page
-(as it appears on PubMed at http://www.pubmed.gov), where 10387067 is the PubMed ID number.
--->
-{{ABSTRACT_PUBMED_10387067}}
-==About this Structure==
-QAL is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QAL OCA].
-==Reference==
-The active site base controls cofactor reactivity in Escherichia coli amine oxidase: x-ray crystallographic studies with mutational variants., Murray JM, Saysell CG, Wilmot CM, Tambyrajah WS, Jaeger J, Knowles PF, Phillips SE, McPherson MJ, Biochemistry. 1999 Jun 29;38(26):8217-27. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10387067 10387067]
 [[Category: Escherichia coli]]
-[[Category: Single protein]]
+[[Category: Large Structures]]
-[[Category: Jaeger, J.]]
+[[Category: Jaeger J]]
-[[Category: Knowles, P F.]]
+[[Category: Knowles PF]]
-[[Category: McPherson, M J.]]
+[[Category: McPherson MJ]]
-[[Category: Murray, J M.]]
+[[Category: Murray JM]]
-[[Category: Phillips, S E.]]
+[[Category: Phillips SE]]
-[[Category: Saysell, C G.]]
+[[Category: Saysell CG]]
-[[Category: Wilmot, C M.]]
+[[Category: Wilmot CM]]
-[[Category: Mushroom shaped homodimer with mainly beta structure. there are 3 small peripheral alpha/beta domains.]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 07:51:37 2008''