1pu6: Difference between revisions

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-[[Image:1pu6.png|left|200px]]
-{{STRUCTURE_1pu6|  PDB=1pu6  |  SCENE=  }}
+==Crystal structure of H.pylori 3-methyladenine DNA glycosylase (MagIII)==
+<StructureSection load='1pu6' size='340' side='right'caption='[[1pu6]], [[Resolution|resolution]] 1.64&Aring;' scene=''>
-===Crystal structure of H.pylori 3-methyladenine DNA glycosylase (MagIII)===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1pu6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PU6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1PU6 FirstGlance]. <br>
-{{ABSTRACT_PUBMED_14517230}}
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.64&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>
-==About this Structure==
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1pu6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pu6 OCA], [https://pdbe.org/1pu6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1pu6 RCSB], [https://www.ebi.ac.uk/pdbsum/1pu6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1pu6 ProSAT]</span></td></tr>
-[[1pu6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PU6 OCA].
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/O25323_HELPY O25323_HELPY] DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity (By similarity).[PIRNR:PIRNR001435]
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pu/1pu6_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1pu6 ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[DNA glycosylate|DNA glycosylate]]
+*[[DNA glycosylase 3D structures|DNA glycosylase 3D structures]]
+__TOC__
-==Reference==
+</StructureSection>
-<ref group="xtra">PMID:014517230</ref><references group="xtra"/>
 [[Category: Helicobacter pylori]]
-[[Category: Eichman, B F.]]
+[[Category: Large Structures]]
-[[Category: Ellenberger, T.]]
+[[Category: Eichman BF]]
-[[Category: Radicella, J P.]]
+[[Category: Ellenberger T]]
-[[Category: Rourke, E J.O.]]
+[[Category: O'Rourke EJ]]
-[[Category: 3-methyladenine]]
+[[Category: Radicella JP]]
-[[Category: Base excision repair]]
-[[Category: Glycosylase]]
-[[Category: Helix-hairpin-helix]]
-[[Category: Hydrolase]]