1pmr: Difference between revisions

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-[[Image:1pmr.png|left|200px]]
-{{STRUCTURE_1pmr|  PDB=1pmr  |  SCENE=  }}
+==LIPOYL DOMAIN FROM THE DIHYDROLIPOYL SUCCINYLTRANSFERASE COMPONENT OF THE 2-OXOGLUTARATE DEHYDROGENASE MULTIENZYME COMPLEX OF ESCHERICHIA COLI, NMR, 25 STRUCTURES==
+<StructureSection load='1pmr' size='340' side='right'caption='[[1pmr]]' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1pmr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. The October 2012 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Citric Acid Cycle''  by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2012_10 10.2210/rcsb_pdb/mom_2012_10]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PMR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1PMR FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1pmr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pmr OCA], [https://pdbe.org/1pmr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1pmr RCSB], [https://www.ebi.ac.uk/pdbsum/1pmr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1pmr ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/ODO2_ECOLI ODO2_ECOLI] The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3).
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pm/1pmr_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1pmr ConSurf].
+<div style="clear:both"></div>
-===LIPOYL DOMAIN FROM THE DIHYDROLIPOYL SUCCINYLTRANSFERASE COMPONENT OF THE 2-OXOGLUTARATE DEHYDROGENASE MULTIENZYME COMPLEX OF ESCHERICHIA COLI, NMR, 25 STRUCTURES===
+==See Also==
+*[[2-oxoglutarate dehydrogenase 3D structures|2-oxoglutarate dehydrogenase 3D structures]]
-{{ABSTRACT_PUBMED_8950276}}
+__TOC__
+</StructureSection>
-==About this Structure==
+[[Category: Citric Acid Cycle]]
-[[1pmr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PMR OCA].
-==Reference==
-<ref group="xtra">PMID:008950276</ref><references group="xtra"/>
-[[Category: Dihydrolipoyllysine-residue succinyltransferase]]
 [[Category: Escherichia coli]]
-[[Category: Broadhurst, R W.]]
+[[Category: Large Structures]]
-[[Category: Howard, M J.]]
+[[Category: RCSB PDB Molecule of the Month]]
-[[Category: Perham, R N.]]
+[[Category: Broadhurst RW]]
-[[Category: Ricaud, P M.]]
+[[Category: Howard MJ]]
-[[Category: Roberts, E L.]]
+[[Category: Perham RN]]
-[[Category: 2-oxoglutarate dehydrogenase]]
+[[Category: Ricaud PM]]
-[[Category: Complex]]
+[[Category: Roberts EL]]
-[[Category: Glycolysis]]
-[[Category: Lipoyl domain]]
-[[Category: Transferase]]