1oqd: Difference between revisions

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-{{Seed}}
-[[Image:1oqd.png|left|200px]]
-<!--
+==Crystal structure of sTALL-1 and BCMA==
-The line below this paragraph, containing "STRUCTURE_1oqd", creates the "Structure Box" on the page.
+<StructureSection load='1oqd' size='340' side='right'caption='[[1oqd]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1oqd]] is a 18 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OQD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OQD FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
--->
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1oqd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1oqd OCA], [https://pdbe.org/1oqd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1oqd RCSB], [https://www.ebi.ac.uk/pdbsum/1oqd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1oqd ProSAT]</span></td></tr>
-{{STRUCTURE_1oqd|  PDB=1oqd  |  SCENE=  }}
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/TN13B_HUMAN TN13B_HUMAN] Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B- and T-cell function and the regulation of humoral immunity. A third B-cell specific BAFF-receptor (BAFFR/BR3) promotes the survival of mature B-cells and the B-cell response.<ref>PMID:10973284</ref>   Isoform 2 seems to inhibit isoform 1 secretion and bioactivity (By similarity).<ref>PMID:10973284</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/oq/1oqd_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1oqd ConSurf].
+<div style="clear:both"></div>
-===Crystal structure of sTALL-1 and BCMA===
+==See Also==
+*[[Tumor necrosis factor ligand superfamily 3D structures|Tumor necrosis factor ligand superfamily 3D structures]]
+== References ==
-<!--
+<references/>
-The line below this paragraph, {{ABSTRACT_PUBMED_12721620}}, adds the Publication Abstract to the page
+__TOC__
-(as it appears on PubMed at http://www.pubmed.gov), where 12721620 is the PubMed ID number.
+</StructureSection>
--->
-{{ABSTRACT_PUBMED_12721620}}
-==About this Structure==
-OQD is a 18 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OQD OCA].
-==Reference==
-<ref group="xtra">PMID:12721620</ref><references group="xtra"/>
 [[Category: Homo sapiens]]
-[[Category: Zhang, G.]]
+[[Category: Large Structures]]
-[[Category: Ligand receptor complex]]
+[[Category: Zhang G]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 21:17:29 2009''