1ohy: Difference between revisions

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OCA

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-[[Image:1ohy.png|left|200px]]
-<!--
+==4-AMINOBUTYRATE-AMINOTRANSFERASE inactivated by gamma-ethynyl GABA==
-The line below this paragraph, containing "STRUCTURE_1ohy", creates the "Structure Box" on the page.
+<StructureSection load='1ohy' size='340' side='right'caption='[[1ohy]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1ohy]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OHY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OHY FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=GEG:(4E)-4-AMINOHEX-4-ENOIC+ACID'>GEG</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>
-{{STRUCTURE_1ohy|  PDB=1ohy  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ohy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ohy OCA], [https://pdbe.org/1ohy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ohy RCSB], [https://www.ebi.ac.uk/pdbsum/1ohy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ohy ProSAT]</span></td></tr>
+</table>
-===4-AMINOBUTYRATE-AMINOTRANSFERASE INACTIVATED BY GAMMA-ETHYNYL GABA===
+== Function ==
+[https://www.uniprot.org/uniprot/GABT_PIG GABT_PIG] Catalyzes the conversion of gamma-aminobutyrate and L-beta-aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respectively. Can also convert delta-aminovalerate and beta-alanine.
+== Evolutionary Conservation ==
-<!--
+[[Image:Consurf_key_small.gif|200px|right]]
-The line below this paragraph, {{ABSTRACT_PUBMED_14534310}}, adds the Publication Abstract to the page
+Check<jmol>
-(as it appears on PubMed at http://www.pubmed.gov), where 14534310 is the PubMed ID number.
+  <jmolCheckbox>
--->
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/oh/1ohy_consurf.spt"</scriptWhenChecked>
-{{ABSTRACT_PUBMED_14534310}}
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
-==About this Structure==
+  </jmolCheckbox>
-[[1ohy]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OHY OCA].
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ohy ConSurf].
+<div style="clear:both"></div>
-==Reference==
+__TOC__
-<ref group="xtra">PMID:14534310</ref><ref group="xtra">PMID:10393538</ref><references group="xtra"/>
+</StructureSection>
-[[Category: 4-aminobutyrate transaminase]]
+[[Category: Large Structures]]
 [[Category: Sus scrofa]]
-[[Category: Schirmer, T.]]
+[[Category: Schirmer T]]
-[[Category: Storici, P.]]
+[[Category: Storici P]]
-[[Category: 4-aminobutyric acid]]
-[[Category: Aminotransferase]]
-[[Category: Antiepileptic drug target]]
-[[Category: Mitochondrion]]
-[[Category: Neurotransmitter degradation]]
-[[Category: Plp-dependent enzyme]]
-[[Category: Transferase]]
-[[Category: Transit peptide]]
-[[Category: Vigabatrin pyridoxal phosphate]]