8qk2: Difference between revisions

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-'''Unreleased structure'''
-The entry 8qk2 is ON HOLD
+==Structure of K.pneumoniae LpxH in complex with EBL-3339==
+<StructureSection load='8qk2' size='340' side='right'caption='[[8qk2]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
-Authors: Sooriyaarachchi, S., Bergfors, T., Jones, T.A., Mowbray, S.L.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[8qk2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8QK2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8QK2 FirstGlance]. <br>
-Description: Structure of K.pneumoniae LpxH in complex with EBL-3339
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=VTF:~{N}-[4-[4-(4-cyano-6-methyl-pyrimidin-2-yl)piperazin-1-yl]sulfonylphenyl]-2-[methyl(methylsulfonyl)amino]benzamide'>VTF</scene></td></tr>
-[[Category: Jones, T.A]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8qk2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8qk2 OCA], [https://pdbe.org/8qk2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8qk2 RCSB], [https://www.ebi.ac.uk/pdbsum/8qk2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8qk2 ProSAT]</span></td></tr>
-[[Category: Mowbray, S.L]]
+</table>
-[[Category: Sooriyaarachchi, S]]
+== Function ==
-[[Category: Bergfors, T]]
+[https://www.uniprot.org/uniprot/LPXH_KLEP7 LPXH_KLEP7] Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.[HAMAP-Rule:MF_00575]
+__TOC__
+</StructureSection>
+[[Category: Klebsiella pneumoniae]]
+[[Category: Large Structures]]
+[[Category: Bergfors T]]
+[[Category: Jones TA]]
+[[Category: Mowbray SL]]
+[[Category: Sooriyaarachchi S]]