1o0r: Difference between revisions

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[[Image:1o0r.png|left|200px]]


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==Crystal structure of the catalytic domain of bovine beta1,4-galactosyltransferase complex with UDP-galactose==
The line below this paragraph, containing "STRUCTURE_1o0r", creates the "Structure Box" on the page.
<StructureSection load='1o0r' size='340' side='right'caption='[[1o0r]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1o0r]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1kyb 1kyb]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O0R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1O0R FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DIO:1,4-DIETHYLENE+DIOXIDE'>DIO</scene>, <scene name='pdbligand=GDU:GALACTOSE-URIDINE-5-DIPHOSPHATE'>GDU</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
{{STRUCTURE_1o0r| PDB=1o0r |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1o0r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1o0r OCA], [https://pdbe.org/1o0r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1o0r RCSB], [https://www.ebi.ac.uk/pdbsum/1o0r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1o0r ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/B4GT1_BOVIN B4GT1_BOVIN] The Golgi complex form catalyzes the production of lactose in the lactating mammary gland and could also be responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.  The cell surface form functions as a recognition molecule during a variety of cell to cell and cell to matrix interactions, as those occurring during development and egg fertilization, by binding to specific oligosaccharide ligands on opposing cells or in the extracellular matrix.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/o0/1o0r_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1o0r ConSurf].
<div style="clear:both"></div>


'''Crystal structure of the catalytic domain of bovine beta1,4-galactosyltransferase complex with UDP-galactose'''
==See Also==
 
*[[Glycosyltransferase 3D structures|Glycosyltransferase 3D structures]]
 
__TOC__
{{ABSTRACT_12051854}}
</StructureSection>
 
==About this Structure==
1O0R is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1kyb 1kyb]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O0R OCA].
[[Category: Bos taurus]]
[[Category: Bos taurus]]
[[Category: N-acetyllactosamine synthase]]
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: Balaji PV]]
[[Category: Balaji, P V.]]
[[Category: Qasba PK]]
[[Category: Qasba, P K.]]
[[Category: Ramakrishnan B]]
[[Category: Ramakrishnan, B.]]
[[Category: Beta1,4-galactosyltransferase]]
[[Category: Conformation ii]]
[[Category: Udp-gal]]
 
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