1mz6: Difference between revisions

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-{{STRUCTURE_1mz6|  PDB=1mz6  |  SCENE=  }}
-===Trypanosoma rangeli sialidase in complex with the inhibitor DANA===
-{{ABSTRACT_PUBMED_10619840}}
-==About this Structure==
+==Trypanosoma rangeli sialidase in complex with the inhibitor DANA==
-[[1mz6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_rangeli Trypanosoma rangeli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MZ6 OCA].
+<StructureSection load='1mz6' size='340' side='right'caption='[[1mz6]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
+== Structural highlights ==
-==Reference==
+<table><tr><td colspan='2'>[[1mz6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_rangeli Trypanosoma rangeli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MZ6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MZ6 FirstGlance]. <br>
-<ref group="xtra">PMID:010619840</ref><references group="xtra"/><references/>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
-[[Category: Exo-alpha-sialidase]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DAN:2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC+ACID'>DAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mz6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mz6 OCA], [https://pdbe.org/1mz6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mz6 RCSB], [https://www.ebi.ac.uk/pdbsum/1mz6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mz6 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/O44049_TRYRA O44049_TRYRA]
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mz/1mz6_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mz6 ConSurf].
+<div style="clear:both"></div>
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
 [[Category: Trypanosoma rangeli]]
-[[Category: Alzari, P M.]]
+[[Category: Alzari PM]]
-[[Category: Amaya, M F.]]
+[[Category: Amaya MF]]
-[[Category: Buschiazzo, A.]]
+[[Category: Buschiazzo A]]
-[[Category: Campetella, O.]]
+[[Category: Campetella O]]
-[[Category: Cremona, M L.]]
+[[Category: Cremona ML]]
-[[Category: Frasch, A C.C.]]
+[[Category: Frasch ACC]]
-[[Category: Paris, G.]]
+[[Category: Paris G]]
-[[Category: Spinelli, S.]]
+[[Category: Spinelli S]]
-[[Category: Tavares, G A.]]
+[[Category: Tavares GA]]
-[[Category: Hydrolase]]
-[[Category: Hydrolase inhibitor]]
-[[Category: Inibitor complex]]
-[[Category: Sialyltransferase]]
-[[Category: Trypanosomal sialidase]]