1m1d: Difference between revisions

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[[Image:1m1d.png|left|200px]]


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==TETRAHYMENA GCN5 WITH BOUND BISUBSTRATE ANALOG INHIBITOR==
The line below this paragraph, containing "STRUCTURE_1m1d", creates the "Structure Box" on the page.
<StructureSection load='1m1d' size='340' side='right'caption='[[1m1d]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1m1d]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae] and [https://en.wikipedia.org/wiki/Tetrahymena_thermophila Tetrahymena thermophila]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M1D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1M1D FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LYX:N-(2-COENZYME+A)-PROPANOYL-LYSINE'>LYX</scene></td></tr>
{{STRUCTURE_1m1d|  PDB=1m1d  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1m1d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m1d OCA], [https://pdbe.org/1m1d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1m1d RCSB], [https://www.ebi.ac.uk/pdbsum/1m1d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1m1d ProSAT]</span></td></tr>
 
</table>
===TETRAHYMENA GCN5 WITH BOUND BISUBSTRATE ANALOG INHIBITOR===
== Function ==
 
[https://www.uniprot.org/uniprot/H3_YEAST H3_YEAST]
 
== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
The line below this paragraph, {{ABSTRACT_PUBMED_12391296}}, adds the Publication Abstract to the page
Check<jmol>
(as it appears on PubMed at http://www.pubmed.gov), where 12391296 is the PubMed ID number.
  <jmolCheckbox>
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/m1/1m1d_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_12391296}}
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 
    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
1M1D is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Tetrahymena_thermophila Tetrahymena thermophila]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M1D OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1m1d ConSurf].
 
<div style="clear:both"></div>
==Reference==
__TOC__
Structure of the GCN5 histone acetyltransferase bound to a bisubstrate inhibitor., Poux AN, Cebrat M, Kim CM, Cole PA, Marmorstein R, Proc Natl Acad Sci U S A. 2002 Oct 29;99(22):14065-70. Epub 2002 Oct 21. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12391296 12391296]
</StructureSection>
[[Category: Protein complex]]
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Tetrahymena thermophila]]
[[Category: Tetrahymena thermophila]]
[[Category: Cebrat, M.]]
[[Category: Cebrat M]]
[[Category: Cole, P A.]]
[[Category: Cole PA]]
[[Category: Kim, C M.]]
[[Category: Kim CM]]
[[Category: Marmorstein, R.]]
[[Category: Marmorstein R]]
[[Category: Poux, A N.]]
[[Category: Poux AN]]
[[Category: Gcn5-related n-acetyltransferase]]
[[Category: Histone acetyltransferase]]
[[Category: Inhibitor complex]]
[[Category: Transcription factor]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul  2 23:00:30 2008''

Latest revision as of 11:30, 10 April 2024

TETRAHYMENA GCN5 WITH BOUND BISUBSTRATE ANALOG INHIBITORTETRAHYMENA GCN5 WITH BOUND BISUBSTRATE ANALOG INHIBITOR

Structural highlights

1m1d is a 4 chain structure with sequence from Saccharomyces cerevisiae and Tetrahymena thermophila. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.2Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

H3_YEAST

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

1m1d, resolution 2.20Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
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