1lvh: Difference between revisions

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-[[Image:1lvh.png|left|200px]]
-{{STRUCTURE_1lvh|  PDB=1lvh  |  SCENE=  }}
+==The Structure of Phosphorylated beta-phosphoglucomutase from Lactoccocus lactis to 2.3 angstrom resolution==
+<StructureSection load='1lvh' size='340' side='right'caption='[[1lvh]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1lvh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Lactococcus_lactis Lactococcus lactis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LVH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LVH FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PHD:ASPARTYL+PHOSPHATE'>PHD</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lvh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lvh OCA], [https://pdbe.org/1lvh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lvh RCSB], [https://www.ebi.ac.uk/pdbsum/1lvh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lvh ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/PGMB_LACLA PGMB_LACLA] Catalyzes the interconversion of D-glucose 1-phosphate (G1P) and D-glucose 6-phosphate (G6P), forming beta-D-glucose 1,6-(bis)phosphate (beta-G16P) as an intermediate. The beta-phosphoglucomutase (Beta-PGM) acts on the beta-C(1) anomer of G1P. Glucose or lactose are used in preference to maltose, which is only utilized after glucose or lactose has been exhausted. It plays a key role in the regulation of the flow of carbohydrate intermediates in glycolysis and the formation of the sugar nucleotide UDP-glucose.<ref>PMID:9084169</ref> <ref>PMID:15005616</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lv/1lvh_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1lvh ConSurf].
+<div style="clear:both"></div>
-===The Structure of Phosphorylated beta-phosphoglucomutase from Lactoccocus lactis to 2.3 angstrom resolution===
+==See Also==
+*[[Beta-phosphoglucomutase|Beta-phosphoglucomutase]]
-{{ABSTRACT_PUBMED_12081483}}
+*[[Beta-phosphoglucomutase 3D structures|Beta-phosphoglucomutase 3D structures]]
+== References ==
-==About this Structure==
+<references/>
-[[1lvh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lactococcus_lactis Lactococcus lactis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LVH OCA].
+__TOC__
+</StructureSection>
-==Reference==
-<ref group="xtra">PMID:012081483</ref><references group="xtra"/>
-[[Category: Beta-phosphoglucomutase]]
 [[Category: Lactococcus lactis]]
-[[Category: Allen, K N.]]
+[[Category: Large Structures]]
-[[Category: Dunaway-Mariano, D.]]
+[[Category: Allen KN]]
-[[Category: Lahiri, S D.]]
+[[Category: Dunaway-Mariano D]]
-[[Category: Zhang, G.]]
+[[Category: Lahiri SD]]
-[[Category: Aspartylphosphate]]
+[[Category: Zhang G]]
-[[Category: Had superfamily]]
-[[Category: Isomerase]]
-[[Category: Phosphoaspartate]]