1lk2: Difference between revisions

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-[[Image:1lk2.png|left|200px]]
-{{STRUCTURE_1lk2|  PDB=1lk2  |  SCENE=  }}
+==1.35A crystal structure of H-2Kb complexed with the GNYSFYAL peptide==
+<StructureSection load='1lk2' size='340' side='right'caption='[[1lk2]], [[Resolution|resolution]] 1.35&Aring;' scene=''>
-===1.35A crystal structure of H-2Kb complexed with the GNYSFYAL peptide===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1lk2]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LK2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LK2 FirstGlance]. <br>
-{{ABSTRACT_PUBMED_14978103}}
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.35&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-==About this Structure==
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lk2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lk2 OCA], [https://pdbe.org/1lk2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lk2 RCSB], [https://www.ebi.ac.uk/pdbsum/1lk2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lk2 ProSAT]</span></td></tr>
-[[1lk2]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LK2 OCA].
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/HA1B_MOUSE HA1B_MOUSE] Involved in the presentation of foreign antigens to the immune system.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lk/1lk2_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1lk2 ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[Beta-2 microglobulin|Beta-2 microglobulin]]
+*[[Beta-2 microglobulin 3D structures|Beta-2 microglobulin 3D structures]]
-*[[Major histocompatibility complex|Major histocompatibility complex]]
+*[[MHC 3D structures|MHC 3D structures]]
+*[[MHC I 3D structures|MHC I 3D structures]]
-==Reference==
+__TOC__
-<ref group="xtra">PMID:014978103</ref><references group="xtra"/>
+</StructureSection>
+[[Category: Large Structures]]
 [[Category: Mus musculus]]
-[[Category: Eisen, H.]]
+[[Category: Eisen H]]
-[[Category: Luz, J G.]]
+[[Category: Luz JG]]
-[[Category: Rudolph, M G.]]
+[[Category: Rudolph MG]]
-[[Category: Wilson, I A.]]
+[[Category: Wilson IA]]
-[[Category: Anisotropic and tls refinement]]
-[[Category: Class i mhc-peptide complex]]
-[[Category: High resolution]]
-[[Category: Immune system]]