1i9b: Difference between revisions

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[[Image:1i9b.png|left|200px]]


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==X-RAY STRUCTURE OF ACETYLCHOLINE BINDING PROTEIN (ACHBP)==
The line below this paragraph, containing "STRUCTURE_1i9b", creates the "Structure Box" on the page.
<StructureSection load='1i9b' size='340' side='right'caption='[[1i9b]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1i9b]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Lymnaea_stagnalis Lymnaea stagnalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I9B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1I9B FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene></td></tr>
{{STRUCTURE_1i9b| PDB=1i9b |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1i9b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1i9b OCA], [https://pdbe.org/1i9b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1i9b RCSB], [https://www.ebi.ac.uk/pdbsum/1i9b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1i9b ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ACHP_LYMST ACHP_LYMST] Binds to acetylcholine. Modulates neuronal synaptic transmission.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i9/1i9b_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1i9b ConSurf].
<div style="clear:both"></div>


===X-RAY STRUCTURE OF ACETYLCHOLINE BINDING PROTEIN (ACHBP)===
==See Also==
 
*[[Acetylcholine binding protein 3D structures|Acetylcholine binding protein 3D structures]]
 
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The line below this paragraph, {{ABSTRACT_PUBMED_11357122}}, adds the Publication Abstract to the page
[[Category: Large Structures]]
(as it appears on PubMed at http://www.pubmed.gov), where 11357122 is the PubMed ID number.
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{{ABSTRACT_PUBMED_11357122}}
 
==About this Structure==
1I9B is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Lymnaea_stagnalis Lymnaea stagnalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I9B OCA].
 
==Reference==
Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors., Brejc K, van Dijk WJ, Klaassen RV, Schuurmans M, van Der Oost J, Smit AB, Sixma TK, Nature. 2001 May 17;411(6835):269-76. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11357122 11357122]
[[Category: Lymnaea stagnalis]]
[[Category: Lymnaea stagnalis]]
[[Category: Single protein]]
[[Category: Brejc K]]
[[Category: Brejc, K.]]
[[Category: Klaassen R]]
[[Category: Dijk, W J.van.]]
[[Category: Schuurmans M]]
[[Category: Klaassen, R.]]
[[Category: Sixma TK]]
[[Category: Oost, J van der.]]
[[Category: Smit AB]]
[[Category: Schuurmans, M.]]
[[Category: Van Dijk WJ]]
[[Category: Sixma, T K.]]
[[Category: Van der Oost J]]
[[Category: Smit, A B.]]
[[Category: Igg fold]]
[[Category: Pentamer]]
 
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