1i2k: Difference between revisions

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-[[Image:1i2k.jpg|left|200px]]
- {{Structure
+==AMINODEOXYCHORISMATE LYASE FROM ESCHERICHIA COLI==
-|PDB= 1i2k |SIZE=350|CAPTION= <scene name='initialview01'>1i2k</scene>, resolution 1.79&Aring;
+<StructureSection load='1i2k' size='340' side='right'caption='[[1i2k]], [[Resolution|resolution]] 1.79&Aring;' scene=''>
-|SITE=
+== Structural highlights ==
-|LIGAND= <scene name='pdbligand=PLP:PYRIDOXAL-5'-PHOSPHATE'>PLP</scene>
+<table><tr><td colspan='2'>[[1i2k]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I2K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1I2K FirstGlance]. <br>
-|ACTIVITY=
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.79&#8491;</td></tr>
-|GENE= PABC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>
-}}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1i2k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1i2k OCA], [https://pdbe.org/1i2k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1i2k RCSB], [https://www.ebi.ac.uk/pdbsum/1i2k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1i2k ProSAT]</span></td></tr>
+</table>
-'''AMINODEOXYCHORISMATE LYASE FROM ESCHERICHIA COLI'''
+== Function ==
+[https://www.uniprot.org/uniprot/PABC_ECOLI PABC_ECOLI] Involved in the biosynthesis of p-aminobenzoate (PABA), a precursor of tetrahydrofolate. Converts 4-amino-4-deoxychorismate into 4-aminobenzoate (PABA) and pyruvate.<ref>PMID:1644759</ref> <ref>PMID:2251281</ref>
+== Evolutionary Conservation ==
-==About this Structure==
+[[Image:Consurf_key_small.gif|200px|right]]
-I2K is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I2K OCA].
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i2/1i2k_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1i2k ConSurf].
+<div style="clear:both"></div>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
 [[Category: Escherichia coli]]
-[[Category: Single protein]]
+[[Category: Large Structures]]
-[[Category: Eisenstein, E.]]
+[[Category: Eisenstein E]]
-[[Category: Fisher, K E.]]
+[[Category: Fisher KE]]
-[[Category: Howard, A J.]]
+[[Category: Howard AJ]]
-[[Category: Jensen, P Y.]]
+[[Category: Jensen PY]]
-[[Category: Ladner, J E.]]
+[[Category: Ladner JE]]
-[[Category: Pachikara, A S.]]
+[[Category: Pachikara AS]]
-[[Category: Parsons, J F.]]
+[[Category: Parsons JF]]
-[[Category: Tordova, M.]]
+[[Category: Tordova M]]
-[[Category: PLP]]
-[[Category: aminodeoxychorismate]]
-[[Category: lyase]]
-[[Category: pabc]]
-[[Category: pyridoxal phosphate]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 11:44:42 2008''