1i2k: Difference between revisions

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[[Image:1i2k.png|left|200px]]


{{STRUCTURE_1i2k|  PDB=1i2k  |  SCENE=  }}
==AMINODEOXYCHORISMATE LYASE FROM ESCHERICHIA COLI==
 
<StructureSection load='1i2k' size='340' side='right'caption='[[1i2k]], [[Resolution|resolution]] 1.79&Aring;' scene=''>
===AMINODEOXYCHORISMATE LYASE FROM ESCHERICHIA COLI===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1i2k]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I2K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1I2K FirstGlance]. <br>
 
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.79&#8491;</td></tr>
==About this Structure==
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>
[[1i2k]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I2K OCA].  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1i2k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1i2k OCA], [https://pdbe.org/1i2k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1i2k RCSB], [https://www.ebi.ac.uk/pdbsum/1i2k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1i2k ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PABC_ECOLI PABC_ECOLI] Involved in the biosynthesis of p-aminobenzoate (PABA), a precursor of tetrahydrofolate. Converts 4-amino-4-deoxychorismate into 4-aminobenzoate (PABA) and pyruvate.<ref>PMID:1644759</ref> <ref>PMID:2251281</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i2/1i2k_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1i2k ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Eisenstein, E.]]
[[Category: Large Structures]]
[[Category: Fisher, K E.]]
[[Category: Eisenstein E]]
[[Category: Howard, A J.]]
[[Category: Fisher KE]]
[[Category: Jensen, P Y.]]
[[Category: Howard AJ]]
[[Category: Ladner, J E.]]
[[Category: Jensen PY]]
[[Category: Pachikara, A S.]]
[[Category: Ladner JE]]
[[Category: Parsons, J F.]]
[[Category: Pachikara AS]]
[[Category: Tordova, M.]]
[[Category: Parsons JF]]
[[Category: Aminodeoxychorismate]]
[[Category: Tordova M]]
[[Category: Lyase]]
[[Category: Pabc]]
[[Category: Pyridoxal phosphate]]

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