1i2e: Difference between revisions

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[[Image:1i2e.png|left|200px]]


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==Ribonuclease T1 V16A mutant, form I==
The line below this paragraph, containing "STRUCTURE_1i2e", creates the "Structure Box" on the page.
<StructureSection load='1i2e' size='340' side='right'caption='[[1i2e]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1i2e]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aspergillus_oryzae Aspergillus oryzae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I2E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1I2E FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2GP:GUANOSINE-2-MONOPHOSPHATE'>2GP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
{{STRUCTURE_1i2e|  PDB=1i2e |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1i2e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1i2e OCA], [https://pdbe.org/1i2e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1i2e RCSB], [https://www.ebi.ac.uk/pdbsum/1i2e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1i2e ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RNT1_ASPOR RNT1_ASPOR]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i2/1i2e_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1i2e ConSurf].
<div style="clear:both"></div>


===Ribonuclease T1 V16A mutant, form I===
==See Also==
 
*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
 
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{{ABSTRACT_PUBMED_11513591}}
 
==About this Structure==
1I2E is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Aspergillus_oryzae Aspergillus oryzae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I2E OCA].
 
==Reference==
Hydrophobic core manipulations in ribonuclease T1., De Vos S, Backmann J, Prevost M, Steyaert J, Loris R, Biochemistry. 2001 Aug 28;40(34):10140-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11513591 11513591]
[[Category: Aspergillus oryzae]]
[[Category: Aspergillus oryzae]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Backmann, J.]]
[[Category: Backmann J]]
[[Category: Loris, R.]]
[[Category: De Vos S]]
[[Category: Steyaert, J.]]
[[Category: Loris R]]
[[Category: Vos, S De.]]
[[Category: Steyaert J]]
[[Category: Cavity creation]]
[[Category: Hydrophobic core packing]]
[[Category: Ribonuclease]]
 
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