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Nonstructural protein 3D structures: Difference between revisions

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**[[1nhu]] – HvNS5B RNA-dependent RNA polymerase residues 2420-2989 – Hepatitis C virus<br />
**[[1nhu]] – HvNS5B RNA-dependent RNA polymerase residues 2420-2989 – Hepatitis C virus<br />
**[[1r7c]], [[1r7d]], [[1r7e]], [[1r7f]], [[1r7g]] - HvNS5A membrane-anchor domain - NMR<br />
**[[1r7c]], [[1r7d]], [[1r7e]], [[1r7f]], [[1r7g]] - HvNS5A membrane-anchor domain - NMR<br />
**[[2gdt]], [[2hsx]] – SvNS1 (mutant) – Sars coronavirus – NMR<br />
**[[8a55]] – SvNS1 N-terminal 11-125 – Sars coronavirus <br />
**[[7eq4]] – SvNS1 N-terminal 11-125 (mutant) <br />
**[[2gdt]], [[2hsx]] – SvNS1 N-terminal (mutant) – NMR<br />
**[[7ci3]], [[7lhq]] – SvNS7A<br />
**[[7bwq]] – SvNS9<br />
**[[2l8k]] – NS7 residues 1454-1575 – Arterivirus - NMR<br />
**[[2l8k]] – NS7 residues 1454-1575 – Arterivirus - NMR<br />
**[[3mtv]] – PrrsvNS1 residues 181-383 – PRRS virus <br />
**[[3mtv]] – PrrsvNS1 residues 181-383 – PRRS virus <br />
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**[[4r05]] – DvNS5 residues 2491-2752 <br />
**[[4r05]] – DvNS5 residues 2491-2752 <br />
**[[4x2z]] – NS3 residues 1174-1483 – Avian infectious bronchitis virus<br />
**[[4x2z]] – NS3 residues 1174-1483 – Avian infectious bronchitis virus<br />
**[[5rhl]], [[6mh3]] – ZvNS3 helicase domain 1681-2115 – Zika virus<br />
**[[4cbg]], [[4cbh]], [[4cbl]], [[4cbm]] – NS3 – Swine fever virus<br />
**[[4cbg]], [[4cbh]], [[4cbl]], [[4cbm]] – NS3 – Swine fever virus<br />
**[[2hwk]] – NS2 – Venzuelan equine encephalitis virus<br />
**[[2hwk]] – VeevNS2 – Venzuelan equine encephalitis virus<br />
**[[8duf]] – VeevNS2 (mutant)<br />
**[[6lp9]] – fipvNSP1 – Feline infectious peritonitis virus<br />
**[[6lp9]] – fipvNSP1 – Feline infectious peritonitis virus<br />
**[[3ub0]] – fipvNSP6 + NSP7 <br />
**[[3ub0]] – fipvNSP6 + NSP7 <br />
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**[[6n9y]] – NS1 – Bluetongue virus<br />
**[[6n9y]] – NS1 – Bluetongue virus<br />
**[[6vdo]] – HcvNS3 (mutant) – Hepacivirus C<br />
**[[6vdo]] – HcvNS3 (mutant) – Hepacivirus C<br />
**[[7ay4]], [[7jno]] – NS3 helicase domain – Tick-borne encephalitis virus<br />
**[[7oj4]], [[7jno]] – NS3 helicase domain – Tick-borne encephalitis virus<br />
**[[7dop]] – CvNS1 – Chicungunya virus - Cryo EM<br />
 
*For Zika virus nonstructural proteins NS2B and NS3 see [[Virus protease]]


*Nonstructural protein complex
*Nonstructural protein complex
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**[[2hye]] – SvNSV + DNA damage-binding protein + cullin-4A + ring-box protein – Simian virus 5<br />
**[[2hye]] – SvNSV + DNA damage-binding protein + cullin-4A + ring-box protein – Simian virus 5<br />
**[[2b5l]] - SvNSV + DNA damage-binding protein<br />
**[[2b5l]] - SvNSV + DNA damage-binding protein<br />
**[[7t70]], [[7t8m]], [[7t8r]], [[7t9y]], [[7ta4]], [[7ta7]], [[7tb2]], [[7tbt]], [[7tc4]] - SvNSV + 3C-like proteinase<br />
**[[1nhv]] – HvNS5B RNA-dependent RNA polymerase residues 2420-2989 + inhibitor<br />
**[[1nhv]] – HvNS5B RNA-dependent RNA polymerase residues 2420-2989 + inhibitor<br />
**[[1dxp]], [[1dy8]], [[1dy9]], [[1w3c]] – HvNS4A + HvHelicase NS3<br />
**[[1dxp]], [[1dy8]], [[1dy9]], [[1w3c]] – HvNS4A + HvHelicase NS3<br />
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**[[4r8r]] – DvNS5 residues 2491-2752 + adenosyl-Met<br />
**[[4r8r]] – DvNS5 residues 2491-2752 + adenosyl-Met<br />
**[[4r8s]] – DvNS5 residues 2491-2752 + sinefungin<br />
**[[4r8s]] – DvNS5 residues 2491-2752 + sinefungin<br />
**[[6ux2]] – ZvNS5 residues 2789-3419 + P113 <br />
**[[6ux2]] – ZvNS5 residues 2789-3419 + P113 - Zika virus<br />
**[[5rhg]], [[5rhh]], [[5rhi]], [[5rhj]], [[5rhk]], [[5rhl]], [[5rhm]], [[5rho]], [[5rhp]], [[5rhq]], [[5rhr]], [[5rhs]], [[5rht]], [[5rhu]], [[5rhv]], [[5rhw]], [[5rhx]] – ZvNS3 + inhibitor <br />
**[[6jpw]] – ZvNS3 + NS2B + peptide <br />
**[[6rwz]], [[6s0j]] – ZvNS3 + ADP<br />
**[[6wcz]] – ZvNS5 + hSTAT2<br />
**[[6wcz]] – ZvNS5 + hSTAT2<br />
**[[6i7p]] – ZvNS5 + SAH<br />
**[[6i7p]] – ZvNS5 + SAH<br />
**[[7x01]] – CvNS1 + inhibitor – Cryo EM<br />
**[[6jim]] – CvNS2 + RNA <br />
**[[7fgg]], [[7fgh]], [[7fgi]] – CvNS1 + nucleotide – Cryo EM<br />
**[[6jim]] – NS2 + RNA – Chicungunya virus<br />
**[[6jim]] – NS2 + RNA – Chicungunya virus<br />
**[[6usm]] – NS1 + MBP – Human parvovirus<br />
**[[6usm]] – NS1 + MBP – Human parvovirus<br />
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*Nonstructural protein NS3 from SARS CoV-2; Domain 1564-1878 (papain-like protease), [[3241-3546 (3C-like proteinase) see [[Virus protease 3D structures]]
*Nonstructural protein NS3 from SARS CoV-2; Domain 1564-1878 (papain-like protease), [[3241-3546 (3C-like proteinase) see [[Virus protease 3D structures]]


**[[2jzd[[, [[2jze]], [[2jzf]], [[2rnk]] – SvNS3 residues 527-651 – NMR<br />
**[[2jzd]], [[2jze]], [[2jzf]], [[2rnk]] – SvNS3 residues 527-651 – NMR<br />
**[[7kag]] – Sv2NS3 Ubl1 domain 819-929<br />
**[[7kag]] – Sv2NS3 Ubl1 domain 819-929<br />
**[[6vxs]], [[6wcf]], [[6wen]], [[6wey]], [[6ywk]], [[6ywm]], [[7kg3]], [[7kqo]], [[7kqw]], [[7kr0]], [[7kr1]] – Sv2NS3 macrodomain 1025-1191<br />
**[[6vxs]], [[6wcf]], [[6wen]], [[6wey]], [[6ywk]], [[6ywm]], [[7kg3]], [[7kqo]], [[7kqw]], [[7kr0]], [[7kr1]] – Sv2NS3 macrodomain 1025-1191<br />
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**[[6yxj]] – Sv2NS3 macrodomain II 1207-1344 + Paip1<br />
**[[6yxj]] – Sv2NS3 macrodomain II 1207-1344 + Paip1<br />


*Other nonstructural protein from SARS CoV-2
*Other nonstructural protein from SARS CoV-2; SV2NS14 is proofreading exoribonuclease


**[[6zlw]], [[6zoj]], [[6zok]], [[6zol]], [[7k5i]] – Sv2NS1 in human 40S ribosome – Cryo EM<br />
**[[6zlw]], [[6zoj]], [[6zok]], [[6zol]], [[7k5i]] – Sv2NS1 in human 40S ribosome – Cryo EM<br />
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**[[6nur]], [[6nus]] – Sv2NS8 residues 4018-4134 + Sv2NS12 residues 4393-5324 – Cryo EM<br />
**[[6nur]], [[6nus]] – Sv2NS8 residues 4018-4134 + Sv2NS12 residues 4393-5324 – Cryo EM<br />
**[[5rob]], [[6jyt]], [[6zsl]], [[7nio]] – SvNS13 <br />
**[[5rob]], [[6jyt]], [[6zsl]], [[7nio]] – SvNS13 <br />
**[[7diy]] – Sv2NS14 residues 5926-6214 + Sv2NS10 residues 4254-4392<br />
**[[5smk]], [[7qgi]] – proofreading exoribonuclease <br />
**[[7diy]] – proofreading exoribonuclease residues 5926-6214 + Sv2NS10 residues 4254-4392<br />
**[[6vww]], [[6w01]], [[6xdh]], [[7kf4]] – Sv2NS15 residues 6453-6798<br />
**[[6vww]], [[6w01]], [[6xdh]], [[7kf4]] – Sv2NS15 residues 6453-6798<br />
**[[6w4h]] – Sv2NS16 residues 6799-7096 + Sv2NS10 residues 4254-4392<br />
**[[6w4h]] – Sv2NS16 residues 6799-7096 + Sv2NS10 residues 4254-4392<br />
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**[[7kri]] – Sv2NS9 residues 4141-4253 + pyrimidine derivative<br />
**[[7kri]] – Sv2NS9 residues 4141-4253 + pyrimidine derivative<br />
**[[7mc5]], [[7mc6]] – Sv2NS10 residues 4254-4392 + proofreading exoribonuclease<br />
**[[7mc5]], [[7mc6]] – Sv2NS10 residues 4254-4392 + proofreading exoribonuclease<br />
**[[7r2v]] – proofreading exoribonuclease + SAH<br />
**[[7qif]] – proofreading exoribonuclease + MeGpppG<br />
**[[5skw]], [[5skx]], [[5sky]], [[5skz]], [[5sl0]], [[5sl1]], [[5sl2]], [[5sl3]], [[5sl4]], [[5sl5]], [[5sl6]], [[5sl7]], [[5sl8]], [[5sl9]], [[5sla]], [[5slb]], [[5slc]], [[5sld]], [[5sle]], [[5slf]], [[5slg]], [[5slh]], [[5sli]], [[5slj]], [[5slk]], [[5sll]], [[5slm]], [[5sln]], [[5slo]], [[5slp]], [[5slq]], [[5slr]], [[5sls]], [[5slt]], [[5slu]] [[5slv]], [[5slw]], [[5slx]], [[5sly]], [[5slz]], [[5sm0]] [[5sm1]], [[5sm2]], [[5sm3]] [[5sm4]], [[5sm5]], [[[5sm6]] [[5sm7]], [[5sm8]], [5sm9]] [[5sma]], [[5smib], [[5smc]] [[5smd]], [[5sme]], [[5smf]], [[5smg]] [[5smh]], [[5smi]], [[5smk]] – proofreading exoribonuclease + inhibitor<br />
**[[7n0b]], [[7n0c]], [[7n0d]] – Sv2NS10 residues 4254-4392 + proofreading exoribonuclease + RNA – Cryo EM<br />
**[[7n0b]], [[7n0c]], [[7n0d]] – Sv2NS10 residues 4254-4392 + proofreading exoribonuclease + RNA – Cryo EM<br />
**[[5rl6]], [[5rl7]], [[5rl8]], [[5rl9]], [[5rlc]], [[5rld]], [[5rle]], [[5rlf]], [[5rlg]], [[5rlh]], [[5rli]], [[5rlj]], [[5rlk]], [[5rll]], [[5rlm]], [[5rln]], [[5rlo]], [[5rlp]], [[5rlq]], [[5rlr]], [[5rls]], [[5rlt]], [[5rlu]], [[5rlv]], [[5rlw]], [[5rly]], [[5rlz]], [[5rm0]], [[5rm1]], [[5rm2]], [[5rm3]], [[5rm4]], [[5rm5]], [[5rm6]], [[5rm7]], [[5rm8]], [[5rm9]], [[5rma]], [[5rmb]], [[5rmc]], [[5rmd]], [[5rme]], [[5rmf]], [[5rmg]], [[5rmh]], [[5rmi]], [[5rmj]], [[5rmk]] [[5rml]], [[5rmm]], [[7nng]] – SvNS13 + inhibitor<br />
**[[5rl6]], [[5rl7]], [[5rl8]], [[5rl9]], [[5rlc]], [[5rld]], [[5rle]], [[5rlf]], [[5rlg]], [[5rlh]], [[5rli]], [[5rlj]], [[5rlk]], [[5rll]], [[5rlm]], [[5rln]], [[5rlo]], [[5rlp]], [[5rlq]], [[5rlr]], [[5rls]], [[5rlt]], [[5rlu]], [[5rlv]], [[5rlw]], [[5rly]], [[5rlz]], [[5rm0]], [[5rm1]], [[5rm2]], [[5rm3]], [[5rm4]], [[5rm5]], [[5rm6]], [[5rm7]], [[5rm8]], [[5rm9]], [[5rma]], [[5rmb]], [[5rmc]], [[5rmd]], [[5rme]], [[5rmf]], [[5rmg]], [[5rmh]], [[5rmi]], [[5rmj]], [[5rmk]] [[5rml]], [[5rmm]], [[7nng]] – SvNS13 + inhibitor<br />

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman
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