4x5i: Difference between revisions

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-'''Unreleased structure'''
-The entry 4x5i is ON HOLD  until Paper Publication
+==ecDHFR complexed with folate and NADP+ at 660 MPa==
+<StructureSection load='4x5i' size='340' side='right'caption='[[4x5i]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4x5i]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X5I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4X5I FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=FOL:FOLIC+ACID'>FOL</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4x5i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x5i OCA], [https://pdbe.org/4x5i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4x5i RCSB], [https://www.ebi.ac.uk/pdbsum/4x5i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4x5i ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/DYR_ECOLI DYR_ECOLI] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
-Authors: Yamada, H., Watanabe, N., Nagae, T.
+==See Also==
+*[[Dihydrofolate reductase 3D structures|Dihydrofolate reductase 3D structures]]
-Description: ecDHFR complexed with folate and NADP+ at 660 MPa
+__TOC__
-[[Category: Unreleased Structures]]
+</StructureSection>
-[[Category: Watanabe, N]]
+[[Category: Escherichia coli K-12]]
-[[Category: Nagae, T]]
+[[Category: Large Structures]]
-[[Category: Yamada, H]]
+[[Category: Nagae T]]
+[[Category: Watanabe N]]
+[[Category: Yamada H]]