3exw: Difference between revisions
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New page: '''Unreleased structure''' The entry 3exw is ON HOLD Authors: Persson, B.D., Reiter, D.M, Arnberg, N, Stehle, T Description: Crystal structure of the human adenovirus type 7 fiber knob... |
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==Crystal structure of the human Adenovirus type 7 fiber knob== | |||
<StructureSection load='3exw' size='340' side='right'caption='[[3exw]], [[Resolution|resolution]] 1.75Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3exw]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_adenovirus_7 Human adenovirus 7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EXW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EXW FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3exw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3exw OCA], [https://pdbe.org/3exw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3exw RCSB], [https://www.ebi.ac.uk/pdbsum/3exw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3exw ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/SPIKE_ADE07 SPIKE_ADE07] Forms spikes that protrude from each vertex of the icosahedral capsid. Interacts with host receptor CD46 to provide virion initial attachment to target cell. Fiber proteins are shed during virus entry, when virus is still at the cell surface.<ref>PMID:11152512</ref> | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ex/3exw_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3exw ConSurf]. | |||
<div style="clear:both"></div> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Human adenovirus 7]] | |||
[[Category: Large Structures]] | |||
[[Category: Arnberg N]] | |||
[[Category: Persson BD]] | |||
[[Category: Reiter DM]] | |||
[[Category: Stehle T]] | |||
Latest revision as of 09:37, 3 April 2024
Crystal structure of the human Adenovirus type 7 fiber knobCrystal structure of the human Adenovirus type 7 fiber knob
Structural highlights
FunctionSPIKE_ADE07 Forms spikes that protrude from each vertex of the icosahedral capsid. Interacts with host receptor CD46 to provide virion initial attachment to target cell. Fiber proteins are shed during virus entry, when virus is still at the cell surface.[1] Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. References
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