1z4u: Difference between revisions

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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

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-{{Seed}}
-[[Image:1z4u.png|left|200px]]
-<!--
+==hepatitis C virus NS5B RNA-dependent RNA polymerase complex with inhibitor PHA-00799585==
-The line below this paragraph, containing "STRUCTURE_1z4u", creates the "Structure Box" on the page.
+<StructureSection load='1z4u' size='340' side='right'caption='[[1z4u]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1z4u]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Hepacivirus_C Hepacivirus C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z4U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Z4U FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PH9:(2Z)-2-[(1-ADAMANTYLCARBONYL)AMINO]-3-[4-(2-BROMOPHENOXY)PHENYL]PROP-2-ENOIC+ACID'>PH9</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-{{STRUCTURE_1z4u|  PDB=1z4u  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1z4u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z4u OCA], [https://pdbe.org/1z4u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1z4u RCSB], [https://www.ebi.ac.uk/pdbsum/1z4u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1z4u ProSAT]</span></td></tr>
+</table>
-===hepatitis C virus NS5B RNA-dependent RNA polymerase complex with inhibitor PHA-00799585===
+== Function ==
+[https://www.uniprot.org/uniprot/O93077_9HEPC O93077_9HEPC]
+== Evolutionary Conservation ==
-<!--
+[[Image:Consurf_key_small.gif|200px|right]]
-The line below this paragraph, {{ABSTRACT_PUBMED_15911260}}, adds the Publication Abstract to the page
+Check<jmol>
-(as it appears on PubMed at http://www.pubmed.gov), where 15911260 is the PubMed ID number.
+  <jmolCheckbox>
--->
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z4/1z4u_consurf.spt"</scriptWhenChecked>
-{{ABSTRACT_PUBMED_15911260}}
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
-==About this Structure==
+  </jmolCheckbox>
-Z4U is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus Hepatitis c virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z4U OCA].
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1z4u ConSurf].
+<div style="clear:both"></div>
-==Reference==
+__TOC__
-<ref group="xtra">PMID:15911260</ref><references group="xtra"/>
+</StructureSection>
-[[Category: Hepatitis c virus]]
+[[Category: Hepacivirus C]]
-[[Category: RNA-directed RNA polymerase]]
+[[Category: Large Structures]]
-[[Category: Anstadt, R.]]
+[[Category: Anstadt R]]
-[[Category: Finzel, B C.]]
+[[Category: Finzel BC]]
-[[Category: Greene, M.]]
+[[Category: Greene M]]
-[[Category: Gross, R J.]]
+[[Category: Gross RJ]]
-[[Category: Harris, M S.]]
+[[Category: Harris MS]]
-[[Category: Mitchell, M A.]]
+[[Category: Mitchell MA]]
-[[Category: Nugent, R.]]
+[[Category: Nugent R]]
-[[Category: Pfefferkorn, J A.]]
+[[Category: Pfefferkorn JA]]
-[[Category: Shelly, J A.]]
+[[Category: Shelly JA]]
-[[Category: Wells, P A.]]
+[[Category: Wells PA]]
-[[Category: Finger]]
-[[Category: Hcv]]
-[[Category: Ns5b]]
-[[Category: Palm]]
-[[Category: Polymerase]]
-[[Category: Thumb]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 08:45:38 2009''