1z4u: Difference between revisions

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[[Image:1z4u.png|left|200px]]


{{STRUCTURE_1z4u|  PDB=1z4u  |  SCENE=  }}
==hepatitis C virus NS5B RNA-dependent RNA polymerase complex with inhibitor PHA-00799585==
 
<StructureSection load='1z4u' size='340' side='right'caption='[[1z4u]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
===hepatitis C virus NS5B RNA-dependent RNA polymerase complex with inhibitor PHA-00799585===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1z4u]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Hepacivirus_C Hepacivirus C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z4U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Z4U FirstGlance]. <br>
{{ABSTRACT_PUBMED_15911260}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PH9:(2Z)-2-[(1-ADAMANTYLCARBONYL)AMINO]-3-[4-(2-BROMOPHENOXY)PHENYL]PROP-2-ENOIC+ACID'>PH9</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1z4u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z4u OCA], [https://pdbe.org/1z4u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1z4u RCSB], [https://www.ebi.ac.uk/pdbsum/1z4u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1z4u ProSAT]</span></td></tr>
[[1z4u]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus Hepatitis c virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z4U OCA].  
</table>
 
== Function ==
==Reference==
[https://www.uniprot.org/uniprot/O93077_9HEPC O93077_9HEPC]  
<ref group="xtra">PMID:015911260</ref><references group="xtra"/>
== Evolutionary Conservation ==
[[Category: Hepatitis c virus]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: RNA-directed RNA polymerase]]
Check<jmol>
[[Category: Anstadt, R.]]
  <jmolCheckbox>
[[Category: Finzel, B C.]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z4/1z4u_consurf.spt"</scriptWhenChecked>
[[Category: Greene, M.]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: Gross, R J.]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Harris, M S.]]
  </jmolCheckbox>
[[Category: Mitchell, M A.]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1z4u ConSurf].
[[Category: Nugent, R.]]
<div style="clear:both"></div>
[[Category: Pfefferkorn, J A.]]
__TOC__
[[Category: Shelly, J A.]]
</StructureSection>
[[Category: Wells, P A.]]
[[Category: Hepacivirus C]]
[[Category: Finger]]
[[Category: Large Structures]]
[[Category: Hcv]]
[[Category: Anstadt R]]
[[Category: Ns5b]]
[[Category: Finzel BC]]
[[Category: Palm]]
[[Category: Greene M]]
[[Category: Polymerase]]
[[Category: Gross RJ]]
[[Category: Thumb]]
[[Category: Harris MS]]
[[Category: Transferase]]
[[Category: Mitchell MA]]
[[Category: Nugent R]]
[[Category: Pfefferkorn JA]]
[[Category: Shelly JA]]
[[Category: Wells PA]]

Latest revision as of 09:21, 3 April 2024

hepatitis C virus NS5B RNA-dependent RNA polymerase complex with inhibitor PHA-00799585hepatitis C virus NS5B RNA-dependent RNA polymerase complex with inhibitor PHA-00799585

Structural highlights

1z4u is a 1 chain structure with sequence from Hepacivirus C. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.8Å
Ligands:, , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

O93077_9HEPC

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

1z4u, resolution 2.80Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
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