1uug: Difference between revisions

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-[[Image:1uug.png|left|200px]]
-{{STRUCTURE_1uug|  PDB=1uug  |  SCENE=  }}
+==ESCHERICHIA COLI URACIL-DNA GLYCOSYLASE:INHIBITOR COMPLEX WITH WILD-TYPE UDG AND WILD-TYPE UGI==
+<StructureSection load='1uug' size='340' side='right'caption='[[1uug]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
-===ESCHERICHIA COLI URACIL-DNA GLYCOSYLASE:INHIBITOR COMPLEX WITH WILD-TYPE UDG AND WILD-TYPE UGI===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1uug]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_phage_PBS2 Bacillus phage PBS2] and [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UUG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UUG FirstGlance]. <br>
-{{ABSTRACT_PUBMED_10080896}}
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1uug FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uug OCA], [https://pdbe.org/1uug PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1uug RCSB], [https://www.ebi.ac.uk/pdbsum/1uug PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1uug ProSAT]</span></td></tr>
-==About this Structure==
+</table>
-[[1uug]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_phage_pbs2 Bacillus phage pbs2] and [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UUG OCA].
+== Function ==
+[https://www.uniprot.org/uniprot/UNG_ECOLI UNG_ECOLI] Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.[HAMAP-Rule:MF_00148]
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uu/1uug_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1uug ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[DNA glycosylate|DNA glycosylate]]
+*[[DNA glycosylase 3D structures|DNA glycosylase 3D structures]]
-*[[Uracil glycosylate inhibitor|Uracil glycosylate inhibitor]]
+*[[Uracil glycosylase inhibitor|Uracil glycosylase inhibitor]]
+__TOC__
-==Reference==
+</StructureSection>
-<ref group="xtra">PMID:010080896</ref><references group="xtra"/>
+[[Category: Bacillus phage PBS2]]
-[[Category: Bacillus phage pbs2]]
+[[Category: Escherichia coli K-12]]
-[[Category: Escherichia coli k-12]]
+[[Category: Large Structures]]
-[[Category: Uridine nucleosidase]]
+[[Category: Arvai AS]]
-[[Category: Arvai, A S.]]
+[[Category: Mol CD]]
-[[Category: Mol, C D.]]
+[[Category: Putnam CD]]
-[[Category: Putnam, C D.]]
+[[Category: Tainer JA]]
-[[Category: Tainer, J A.]]
-[[Category: Dna base excision repair]]
-[[Category: Hydrolase]]
-[[Category: Protein inhibitor]]
-[[Category: Protein mimicry of dna]]
-[[Category: Replication]]