1ulg: Difference between revisions

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[[Image:1ulg.png|left|200px]]


{{STRUCTURE_1ulg|  PDB=1ulg  |  SCENE=  }}
==CGL2 in complex with Thomsen-Friedenreich antigen==
 
<StructureSection load='1ulg' size='340' side='right'caption='[[1ulg]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
===CGL2 in complex with Thomsen-Friedenreich antigen===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1ulg]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Coprinopsis_cinerea Coprinopsis cinerea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ULG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ULG FirstGlance]. <br>
{{ABSTRACT_PUBMED_15062091}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=NGA:N-ACETYL-D-GALACTOSAMINE'>NGA</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ulg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ulg OCA], [https://pdbe.org/1ulg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ulg RCSB], [https://www.ebi.ac.uk/pdbsum/1ulg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ulg ProSAT]</span></td></tr>
[[1ulg]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Coprinopsis_cinerea Coprinopsis cinerea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ULG OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/CGL2_COPCI CGL2_COPCI] Binds lactose. May play a role in fruiting body formation.<ref>PMID:8999822</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ul/1ulg_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ulg ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Galectin|Galectin]]
*[[Galectin 3D structures|Galectin 3D structures]]
 
== References ==
==Reference==
<references/>
<ref group="xtra">PMID:015062091</ref><references group="xtra"/>
__TOC__
</StructureSection>
[[Category: Coprinopsis cinerea]]
[[Category: Coprinopsis cinerea]]
[[Category: Aebi, M.]]
[[Category: Large Structures]]
[[Category: Ban, N.]]
[[Category: Aebi M]]
[[Category: Haebel, P W.]]
[[Category: Ban N]]
[[Category: Kuenzler, M.]]
[[Category: Haebel PW]]
[[Category: Kues, U.]]
[[Category: Kuenzler M]]
[[Category: Walser, P J.]]
[[Category: Kues U]]
[[Category: Beta-galactoside binding lectin]]
[[Category: Walser PJ]]
[[Category: Galectin]]
[[Category: Lectin]]
[[Category: Sugar binding]]
[[Category: Sugar binding protein]]

Latest revision as of 09:16, 3 April 2024

CGL2 in complex with Thomsen-Friedenreich antigenCGL2 in complex with Thomsen-Friedenreich antigen

Structural highlights

1ulg is a 4 chain structure with sequence from Coprinopsis cinerea. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.2Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

CGL2_COPCI Binds lactose. May play a role in fruiting body formation.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

References

  1. ↑ Cooper DN, Boulianne RP, Charlton S, Farrell EM, Sucher A, Lu BC. Fungal galectins, sequence and specificity of two isolectins from Coprinus cinereus. J Biol Chem. 1997 Jan 17;272(3):1514-21. PMID:8999822

1ulg, resolution 2.20Å

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