1je1: Difference between revisions

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-[[Image:1je1.png|left|200px]]
-{{STRUCTURE_1je1|  PDB=1je1  |  SCENE=  }}
+==5'-DEOXY-5'-METHYLTHIOADENOSINE PHOSPHORYLASE COMPLEX WITH GUANOSINE AND SULFATE==
+<StructureSection load='1je1' size='340' side='right'caption='[[1je1]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1je1]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharolobus_solfataricus Saccharolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JE1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JE1 FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GMP:GUANOSINE'>GMP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1je1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1je1 OCA], [https://pdbe.org/1je1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1je1 RCSB], [https://www.ebi.ac.uk/pdbsum/1je1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1je1 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/PNPH_SACS2 PNPH_SACS2] Cleavage of guanosine or inosine to respective bases and sugar-1-phosphate molecules. Cleaves inosine, guanosine, and adenosine with a better efficiency than MTA.<ref>PMID:15819883</ref> <ref>PMID:7929153</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/je/1je1_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1je1 ConSurf].
+<div style="clear:both"></div>
-===5'-DEOXY-5'-METHYLTHIOADENOSINE PHOSPHORYLASE COMPLEX WITH GUANOSINE AND SULFATE===
+==See Also==
+*[[5'-deoxy-5'-methylthioadenosine phosphorylase 3D structures|5'-deoxy-5'-methylthioadenosine phosphorylase 3D structures]]
-{{ABSTRACT_PUBMED_11489901}}
+== References ==
+<references/>
-==About this Structure==
+__TOC__
-[[1je1]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JE1 OCA].
+</StructureSection>
+[[Category: Large Structures]]
-==Reference==
+[[Category: Saccharolobus solfataricus]]
-<ref group="xtra">PMID:011489901</ref><references group="xtra"/>
+[[Category: Appleby TC]]
-[[Category: S-methyl-5'-thioadenosine phosphorylase]]
+[[Category: Cacciapuoti G]]
-[[Category: Sulfolobus solfataricus]]
+[[Category: Ealick SE]]
-[[Category: Appleby, T C.]]
+[[Category: Mathews II]]
-[[Category: Cacciapuoti, G.]]
+[[Category: Porcelli M]]
-[[Category: Ealick, S E.]]
-[[Category: Mathews, I I.]]
-[[Category: Porcelli, M.]]
-[[Category: Alpha-beta protein]]
-[[Category: Transferase]]