1en7: Difference between revisions

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[[Image:1en7.png|left|200px]]


{{STRUCTURE_1en7|  PDB=1en7  |  SCENE=  }}
==ENDONUCLEASE VII (ENDOVII) FROM PHAGE T4==
 
<StructureSection load='1en7' size='340' side='right'caption='[[1en7]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
===ENDONUCLEASE VII (ENDOVII) FROM PHAGE T4===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1en7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EN7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EN7 FirstGlance]. <br>
{{ABSTRACT_PUBMED_10075917}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1en7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1en7 OCA], [https://pdbe.org/1en7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1en7 RCSB], [https://www.ebi.ac.uk/pdbsum/1en7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1en7 ProSAT]</span></td></tr>
[[1en7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EN7 OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/END7_BPT4 END7_BPT4] Cleaves DNA cruciform and Y-structures as well as heteroduplex loops. Resolves Holliday junctions, recognizes a broad spectrum of DNA substrates ranging from branched DNAs to single base mismatches.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/en/1en7_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1en7 ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Endonuclease|Endonuclease]]
*[[Endonuclease 3D structures|Endonuclease 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:010075917</ref><ref group="xtra">PMID:011327769</ref><references group="xtra"/>
[[Category: Escherichia virus T4]]
[[Category: Crossover junction endodeoxyribonuclease]]
[[Category: Large Structures]]
[[Category: Enterobacteria phage t4]]
[[Category: Raaijmakers H]]
[[Category: Raaijmakers, H.]]
[[Category: Suck D]]
[[Category: Suck, D.]]
[[Category: Toro I]]
[[Category: Toro, I.]]
[[Category: Vix O]]
[[Category: Vix, O.]]
[[Category: Dnase]]
[[Category: Endonuclease]]
[[Category: Holliday junction]]
[[Category: Hydrolase]]
[[Category: Resolvase]]

Latest revision as of 08:58, 3 April 2024

ENDONUCLEASE VII (ENDOVII) FROM PHAGE T4ENDONUCLEASE VII (ENDOVII) FROM PHAGE T4

Structural highlights

1en7 is a 2 chain structure with sequence from Escherichia virus T4. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.4Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

END7_BPT4 Cleaves DNA cruciform and Y-structures as well as heteroduplex loops. Resolves Holliday junctions, recognizes a broad spectrum of DNA substrates ranging from branched DNAs to single base mismatches.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1en7, resolution 2.40Å

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