1cm3: Difference between revisions

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[[Image:1cm3.png|left|200px]]


{{STRUCTURE_1cm3| PDB=1cm3 | SCENE= }}
==HIS15ASP HPR FROM E. COLI==
<StructureSection load='1cm3' size='340' side='right'caption='[[1cm3]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1cm3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CM3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1CM3 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1cm3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cm3 OCA], [https://pdbe.org/1cm3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1cm3 RCSB], [https://www.ebi.ac.uk/pdbsum/1cm3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1cm3 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PTHP_ECOLI PTHP_ECOLI] General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the permease (enzymes II/III).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cm/1cm3_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1cm3 ConSurf].
<div style="clear:both"></div>


===HIS15ASP HPR FROM E. COLI===
==See Also==
 
*[[Phosphocarrier protein HPr 3D structures|Phosphocarrier protein HPr 3D structures]]
{{ABSTRACT_PUBMED_10419492}}
__TOC__
 
</StructureSection>
==About this Structure==
[[1cm3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CM3 OCA].
 
==Reference==
<ref group="xtra">PMID:010419492</ref><references group="xtra"/>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Delbaere, L T.J.]]
[[Category: Large Structures]]
[[Category: Napper, S.]]
[[Category: Delbaere LTJ]]
[[Category: Waygood, E B.]]
[[Category: Napper S]]
[[Category: Phosphotransferase]]
[[Category: Waygood EB]]
[[Category: Transferase]]

Latest revision as of 08:57, 3 April 2024

HIS15ASP HPR FROM E. COLIHIS15ASP HPR FROM E. COLI

Structural highlights

1cm3 is a 1 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.6Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

PTHP_ECOLI General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the permease (enzymes II/III).

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1cm3, resolution 1.60Å

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