1b1x: Difference between revisions

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-[[Image:1b1x.png|left|200px]]
-{{STRUCTURE_1b1x|  PDB=1b1x  |  SCENE=  }}
+==STRUCTURE OF DIFERRIC MARE LACTOFERRIN AT 2.62A RESOLUTION==
+<StructureSection load='1b1x' size='340' side='right'caption='[[1b1x]], [[Resolution|resolution]] 2.62&Aring;' scene=''>
-===STRUCTURE OF DIFERRIC MARE LACTOFERRIN AT 2.62A RESOLUTION===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1b1x]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Equus_caballus Equus caballus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1bgr 1bgr]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B1X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1B1X FirstGlance]. <br>
-{{ABSTRACT_PUBMED_10366507}}
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.62&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CO3:CARBONATE+ION'>CO3</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene></td></tr>
-==About this Structure==
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1b1x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b1x OCA], [https://pdbe.org/1b1x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1b1x RCSB], [https://www.ebi.ac.uk/pdbsum/1b1x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1b1x ProSAT]</span></td></tr>
-[[1b1x]] is a 1 chain structure of [[Lactoferrin]] with sequence from [http://en.wikipedia.org/wiki/Equus_caballus Equus caballus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1bgr 1bgr]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B1X OCA].
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/TRFL_HORSE TRFL_HORSE] Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate.  The lactotransferrin transferrin-like domain 1 functions as a serine protease of the peptidase S60 family that cuts arginine rich regions. This function contributes to the antimicrobial activity (By similarity).
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b1/1b1x_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1b1x ConSurf].
+<div style="clear:both"></div>
 ==See Also==
 *[[Lactoferrin|Lactoferrin]]
+__TOC__
-==Reference==
+</StructureSection>
-<ref group="xtra">PMID:010366507</ref><references group="xtra"/>
 [[Category: Equus caballus]]
-[[Category: Sharma, A K.]]
+[[Category: Large Structures]]
-[[Category: Singh, T P.]]
+[[Category: Sharma AK]]
-[[Category: Srinivasan, A.]]
+[[Category: Singh TP]]
-[[Category: Antibacterial]]
+[[Category: Srinivasan A]]
-[[Category: Iron binding protein]]
-[[Category: Lactoferrin]]
-[[Category: Metal binding protein]]