1aq4: Difference between revisions

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[[Image:1aq4.png|left|200px]]


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==STRUCTURE OF A MS2 COAT PROTEIN MUTANT IN COMPLEX WITH AN RNA OPERATOR==
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<StructureSection load='1aq4' size='340' side='right'caption='[[1aq4]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
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== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1aq4]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_phage_MS2 Escherichia phage MS2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AQ4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1AQ4 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1aq4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1aq4 OCA], [https://pdbe.org/1aq4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1aq4 RCSB], [https://www.ebi.ac.uk/pdbsum/1aq4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1aq4 ProSAT]</span></td></tr>
{{STRUCTURE_1aq4| PDB=1aq4 |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/CAPSD_BPMS2 CAPSD_BPMS2] Self-assembles to form the T=3 icosahedral virus shell that protects the viral nucleic acid. Acts as a translational repressor by binding with high specificity to a single stem-loop structure in the genomic RNA that contains the initiation codon of the gene for the viral replicase. Involved in virus assembly through the interaction between a capsid protein dimer and the multiple packaging signals present in the RNA genome.<ref>PMID:16531233</ref> <ref>PMID:18662904</ref> <ref>PMID:26608810</ref> <ref>PMID:8254664</ref> <ref>PMID:9245600</ref> <ref>PMID:9469847</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/aq/1aq4_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1aq4 ConSurf].
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===STRUCTURE OF A MS2 COAT PROTEIN MUTANT IN COMPLEX WITH AN RNA OPERATOR===
==See Also==
 
*[[Virus coat proteins 3D structures|Virus coat proteins 3D structures]]
 
== References ==
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[[Category: Escherichia phage MS2]]
{{ABSTRACT_PUBMED_9469847}}
[[Category: Large Structures]]
 
[[Category: Liljas L]]
==About this Structure==
[[Category: Stonehouse NJ]]
1AQ4 is a 5 chains structure of sequences from [http://en.wikipedia.org/wiki/Enterobacterio_phage_ms2 Enterobacterio phage ms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AQ4 OCA].
[[Category: Valegard K]]
 
[[Category: Van Den Worm SH]]
==Reference==
<ref group="xtra">PMID:9469847</ref><references group="xtra"/>
[[Category: Enterobacterio phage ms2]]
[[Category: Stonehouse, N.]]
[[Category: Valegard, K.]]
[[Category: Worm, L Liljas S Van Den.]]
[[Category: Coat protein]]
[[Category: Icosahedral virus]]
[[Category: Rna fragment]]
[[Category: Rna-binding]]
[[Category: Viral protein capsid]]
 
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