1gxh: Difference between revisions

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New page: left|200px<br /><applet load="1gxh" size="450" color="white" frame="true" align="right" spinBox="true" caption="1gxh" /> '''COLICIN E8 DNASE IMMUNITY PROTEIN: IM8'''<br...
 
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[[Image:1gxh.gif|left|200px]]<br /><applet load="1gxh" size="450" color="white" frame="true" align="right" spinBox="true"
caption="1gxh" />
'''COLICIN E8 DNASE IMMUNITY PROTEIN: IM8'''<br />


==About this Structure==
==Colicin E8 DNAse immunity protein: Im8==
1GXH is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. This structure superseeds the now removed PDB entry 1IMY. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1GXH OCA].  
<StructureSection load='1gxh' size='340' side='right'caption='[[1gxh]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1gxh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1imy 1imy]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GXH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GXH FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gxh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gxh OCA], [https://pdbe.org/1gxh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gxh RCSB], [https://www.ebi.ac.uk/pdbsum/1gxh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gxh ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/IMM8_ECOLX IMM8_ECOLX] This protein is able to protect a cell, which harbors the plasmid ColE8 encoding colicin E8, against colicin E8, it binds specifically to the DNase-type colicin and inhibits its bactericidal activity.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gx/1gxh_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1gxh ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[Colicin immunity protein 3D structures|Colicin immunity protein 3D structures]]
__TOC__
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Boetzel, R.]]
[[Category: Boetzel R]]
[[Category: Czisch, M.]]
[[Category: Czisch M]]
[[Category: James, R.]]
[[Category: James R]]
[[Category: Kleanthous, C.]]
[[Category: Kleanthous C]]
[[Category: Leduff, C.S.]]
[[Category: Leduff CS]]
[[Category: Moore, G.R.]]
[[Category: Moore GR]]
[[Category: Videler, H.]]
[[Category: Videler H]]
[[Category: bacteriocin immunity]]
[[Category: dnase inhibitor]]
[[Category: inhibitor protein of dnase colicin e8]]
[[Category: plasmid]]
 
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Nov 20 16:20:02 2007''

Latest revision as of 14:25, 27 March 2024

Colicin E8 DNAse immunity protein: Im8Colicin E8 DNAse immunity protein: Im8

Structural highlights

1gxh is a 1 chain structure with sequence from Escherichia coli. This structure supersedes the now removed PDB entry 1imy. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Solution NMR
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

IMM8_ECOLX This protein is able to protect a cell, which harbors the plasmid ColE8 encoding colicin E8, against colicin E8, it binds specifically to the DNase-type colicin and inhibits its bactericidal activity.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

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