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[[Image:1gxh.png|left|200px]]


{{STRUCTURE_1gxh|  PDB=1gxh  |  SCENE= }}
==Colicin E8 DNAse immunity protein: Im8==
 
<StructureSection load='1gxh' size='340' side='right'caption='[[1gxh]]' scene=''>
===COLICIN E8 DNASE IMMUNITY PROTEIN: IM8===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1gxh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1imy 1imy]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GXH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GXH FirstGlance]. <br>
 
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gxh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gxh OCA], [https://pdbe.org/1gxh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gxh RCSB], [https://www.ebi.ac.uk/pdbsum/1gxh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gxh ProSAT]</span></td></tr>
[[1gxh]] is a 1 chain structure of [[Colicin Immunity Protein]] with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1imy 1imy]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GXH OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/IMM8_ECOLX IMM8_ECOLX] This protein is able to protect a cell, which harbors the plasmid ColE8 encoding colicin E8, against colicin E8, it binds specifically to the DNase-type colicin and inhibits its bactericidal activity.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gx/1gxh_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1gxh ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Colicin Immunity Protein|Colicin Immunity Protein]]
*[[Colicin immunity protein 3D structures|Colicin immunity protein 3D structures]]
__TOC__
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Boetzel, R.]]
[[Category: Large Structures]]
[[Category: Czisch, M.]]
[[Category: Boetzel R]]
[[Category: James, R.]]
[[Category: Czisch M]]
[[Category: Kleanthous, C.]]
[[Category: James R]]
[[Category: Leduff, C S.]]
[[Category: Kleanthous C]]
[[Category: Moore, G R.]]
[[Category: Leduff CS]]
[[Category: Videler, H.]]
[[Category: Moore GR]]
[[Category: Bacteriocin immunity]]
[[Category: Videler H]]
[[Category: Dnase inhibitor]]
[[Category: Inhibitor]]
[[Category: Inhibitor protein of dnase colicin e8]]

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