1grx: Difference between revisions
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==STRUCTURE OF E. COLI GLUTAREDOXIN== | |||
<StructureSection load='1grx' size='340' side='right'caption='[[1grx]]' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[1grx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GRX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GRX FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1grx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1grx OCA], [https://pdbe.org/1grx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1grx RCSB], [https://www.ebi.ac.uk/pdbsum/1grx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1grx ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/GLRX1_ECOLI GLRX1_ECOLI] The disulfide bond functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase. In addition, it is also involved in reducing some disulfide bonds in a coupled system with glutathione reductase. | |||
== Evolutionary Conservation == | |||
< | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gr/1grx_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
== | </jmolCheckbox> | ||
[[1grx]] is a 1 chain structure with sequence from [ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1grx ConSurf]. | ||
<div style="clear:both"></div> | |||
== | __TOC__ | ||
< | </StructureSection> | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Billeter M]] | ||
[[Category: | [[Category: Bushweller JH]] | ||
[[Category: | [[Category: Holmgren LA]] | ||
[[Category: | [[Category: Wuthrich K]] | ||
Latest revision as of 14:24, 27 March 2024
STRUCTURE OF E. COLI GLUTAREDOXINSTRUCTURE OF E. COLI GLUTAREDOXIN
Structural highlights
FunctionGLRX1_ECOLI The disulfide bond functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase. In addition, it is also involved in reducing some disulfide bonds in a coupled system with glutathione reductase. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. |
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