1gos: Difference between revisions

New page: {{Seed}} left|200px <!-- The line below this paragraph, containing "STRUCTURE_1gos", creates the "Structure Box" on the page. You may change the PDB parameter (which se...
 
No edit summary
 
(11 intermediate revisions by the same user not shown)
Line 1: Line 1:
{{Seed}}
[[Image:1gos.png|left|200px]]


<!--
==Human Monoamine Oxidase B==
The line below this paragraph, containing "STRUCTURE_1gos", creates the "Structure Box" on the page.
<StructureSection load='1gos' size='340' side='right'caption='[[1gos]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1gos]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GOS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GOS FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=NYP:N-[(E)-METHYL](PHENYL)-N-[(E)-2-PROPENYLIDENE]METHANAMINIUM'>NYP</scene></td></tr>
{{STRUCTURE_1gos| PDB=1gos |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gos FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gos OCA], [https://pdbe.org/1gos PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gos RCSB], [https://www.ebi.ac.uk/pdbsum/1gos PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gos ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/AOFB_HUMAN AOFB_HUMAN] Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/go/1gos_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1gos ConSurf].
<div style="clear:both"></div>


===HUMAN MONOAMINE OXIDASE B===
==See Also==
 
*[[Monoamine oxidase|Monoamine oxidase]]
 
__TOC__
<!--
</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_11753429}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 11753429 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_11753429}}
 
==About this Structure==
1GOS is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GOS OCA].
 
==Reference==
<ref group="xtra">PMID:11753429</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Binda, C.]]
[[Category: Large Structures]]
[[Category: Edmondson, D E.]]
[[Category: Binda C]]
[[Category: Hubalek, F.]]
[[Category: Edmondson DE]]
[[Category: Mattevi, A.]]
[[Category: Hubalek F]]
[[Category: Newton-Vinson, P.]]
[[Category: Mattevi A]]
[[Category: Fad-containing amine oxidase]]
[[Category: Newton-Vinson P]]
[[Category: Oxidoreductase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Aug 16 05:30:05 2010''

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA