1gnh: Difference between revisions

← Older edit

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-[[Image:1gnh.png|left|200px]]
-{{STRUCTURE_1gnh|  PDB=1gnh  |  SCENE=  }}
+==HUMAN C-REACTIVE PROTEIN==
+<StructureSection load='1gnh' size='340' side='right'caption='[[1gnh]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1gnh]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GNH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GNH FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gnh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gnh OCA], [https://pdbe.org/1gnh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gnh RCSB], [https://www.ebi.ac.uk/pdbsum/1gnh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gnh ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/CRP_HUMAN CRP_HUMAN] Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gn/1gnh_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1gnh ConSurf].
+<div style="clear:both"></div>
-===HUMAN C-REACTIVE PROTEIN===
+==See Also==
+*[[C-reactive protein|C-reactive protein]]
-{{ABSTRACT_PUBMED_8599761}}
+__TOC__
+</StructureSection>
-==About this Structure==
-[[1gnh]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GNH OCA].
-==Reference==
-<ref group="xtra">PMID:008599761</ref><references group="xtra"/>
 [[Category: Homo sapiens]]
-[[Category: Bloomer, A C.]]
+[[Category: Large Structures]]
-[[Category: Cheetham, G M.T.]]
+[[Category: Bloomer AC]]
-[[Category: Greenhough, T J.]]
+[[Category: Cheetham GMT]]
-[[Category: Holden, D.]]
+[[Category: Greenhough TJ]]
-[[Category: Myles, D A.]]
+[[Category: Holden D]]
-[[Category: Pepys, M B.]]
+[[Category: Myles DA]]
-[[Category: Shrive, A K.]]
+[[Category: Pepys MB]]
-[[Category: Turnell, W G.]]
+[[Category: Shrive AK]]
-[[Category: Volanakis, J E.]]
+[[Category: Turnell WG]]
-[[Category: Acute-phase protein]]
+[[Category: Volanakis JE]]
-[[Category: Acute-phase reactant]]
-[[Category: Pentraxin]]