1gm7: Difference between revisions
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== | ==Crystal structures of penicillin acylase enzyme-substrate complexes: Structural insights into the catalytic mechanism== | ||
[[1gm7]] is a 2 chain structure with sequence from [ | <StructureSection load='1gm7' size='340' side='right'caption='[[1gm7]], [[Resolution|resolution]] 1.45Å' scene=''> | ||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[1gm7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GM7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GM7 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.45Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PNN:PENICILLIN+G'>PNN</scene>, <scene name='pdbligand=SME:METHIONINE+SULFOXIDE'>SME</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gm7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gm7 OCA], [https://pdbe.org/1gm7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gm7 RCSB], [https://www.ebi.ac.uk/pdbsum/1gm7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gm7 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/PAC_ECOLX PAC_ECOLX] | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gm/1gm7_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1gm7 ConSurf]. | |||
<div style="clear:both"></div> | |||
==See Also== | ==See Also== | ||
*[[Penicillin acylase|Penicillin acylase]] | *[[Penicillin acylase|Penicillin acylase]] | ||
__TOC__ | |||
</StructureSection> | |||
[[Category: Escherichia coli]] | |||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Brannigan JA]] | ||
[[Category: Brannigan | [[Category: Dodson GG]] | ||
[[Category: Dodson | [[Category: McVey CE]] | ||
[[Category: McVey | [[Category: Walsh MA]] | ||
[[Category: Walsh | [[Category: Wilson KS]] | ||
[[Category: Wilson | |||
Latest revision as of 14:22, 27 March 2024
Crystal structures of penicillin acylase enzyme-substrate complexes: Structural insights into the catalytic mechanismCrystal structures of penicillin acylase enzyme-substrate complexes: Structural insights into the catalytic mechanism
Structural highlights
FunctionEvolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also |
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