1gkf: Difference between revisions

From Proteopedia
Jump to navigation Jump to search
← Older edit
m Protected "1gkf" [edit=sysop:move=sysop]
No edit summary
 
(8 intermediate revisions by the same user not shown)
Line 1: Line 1:
[[Image:1gkf.png|left|200px]]


<!--
==Crystal structures of penicillin acylase enzyme-substrate complexes: Structural insights into the catalytic mechanism==
The line below this paragraph, containing "STRUCTURE_1gkf", creates the "Structure Box" on the page.
<StructureSection load='1gkf' size='340' side='right'caption='[[1gkf]], [[Resolution|resolution]] 1.41&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1gkf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GKF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GKF FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.41&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SME:METHIONINE+SULFOXIDE'>SME</scene></td></tr>
{{STRUCTURE_1gkf|  PDB=1gkf |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gkf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gkf OCA], [https://pdbe.org/1gkf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gkf RCSB], [https://www.ebi.ac.uk/pdbsum/1gkf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gkf ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PAC_ECOLX PAC_ECOLX]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gk/1gkf_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1gkf ConSurf].
<div style="clear:both"></div>


===CRYSTAL STRUCTURES OF PENICILLIN ACYLASE ENZYME-SUBSTRATE COMPLEXES: STRUCTURAL INSIGHTS INTO THE CATALYTIC MECHANISM===
==See Also==
 
*[[Penicillin acylase|Penicillin acylase]]
 
__TOC__
<!--
</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_11601852}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 11601852 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_11601852}}
 
==About this Structure==
[[1gkf]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GKF OCA].
 
==Reference==
<ref group="xtra">PMID:11601852</ref><ref group="xtra">PMID:2217137</ref><references group="xtra"/>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Penicillin amidase]]
[[Category: Large Structures]]
[[Category: Brannigan, J A.]]
[[Category: Brannigan JA]]
[[Category: Dodson, G G.]]
[[Category: Dodson GG]]
[[Category: Mcvey, C E.]]
[[Category: McVey CE]]
[[Category: Walsh, M A.]]
[[Category: Walsh MA]]
[[Category: Wilson, K S.]]
[[Category: Wilson KS]]
[[Category: Antibiotic resistance]]

Latest revision as of 14:22, 27 March 2024

Crystal structures of penicillin acylase enzyme-substrate complexes: Structural insights into the catalytic mechanismCrystal structures of penicillin acylase enzyme-substrate complexes: Structural insights into the catalytic mechanism

Structural highlights

1gkf is a 2 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.41Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

PAC_ECOLX

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1gkf, resolution 1.41Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
Retrieved from "https://proteopedia.openfox.io/wiki/index.php?title=1gkf&oldid=4114452"