1fw6: Difference between revisions

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-{{Seed}}
-[[Image:1fw6.png|left|200px]]
-<!--
+==CRYSTAL STRUCTURE OF A TAQ MUTS-DNA-ADP TERNARY COMPLEX==
-The line below this paragraph, containing "STRUCTURE_1fw6", creates the "Structure Box" on the page.
+<StructureSection load='1fw6' size='340' side='right'caption='[[1fw6]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1fw6]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_aquaticus Thermus aquaticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FW6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FW6 FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-{{STRUCTURE_1fw6|  PDB=1fw6  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fw6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fw6 OCA], [https://pdbe.org/1fw6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1fw6 RCSB], [https://www.ebi.ac.uk/pdbsum/1fw6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fw6 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/MUTS_THEAQ MUTS_THEAQ] This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fw/1fw6_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1fw6 ConSurf].
+<div style="clear:both"></div>
-===CRYSTAL STRUCTURE OF A TAQ MUTS-DNA-ADP TERNARY COMPLEX===
+==See Also==
+*[[DNA mismatch repair protein 3D structures|DNA mismatch repair protein 3D structures]]
+__TOC__
-<!--
+</StructureSection>
-The line below this paragraph, {{ABSTRACT_PUBMED_11172706}}, adds the Publication Abstract to the page
+[[Category: Large Structures]]
-(as it appears on PubMed at http://www.pubmed.gov), where 11172706 is the PubMed ID number.
--->
-{{ABSTRACT_PUBMED_11172706}}
-==About this Structure==
-FW6 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_aquaticus Thermus aquaticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FW6 OCA].
-==Reference==
-Composite active site of an ABC ATPase: MutS uses ATP to verify mismatch recognition and authorize DNA repair., Junop MS, Obmolova G, Rausch K, Hsieh P, Yang W, Mol Cell. 2001 Jan;7(1):1-12. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11172706 11172706]
-[[Category: Single protein]]
 [[Category: Thermus aquaticus]]
-[[Category: Hsieh, P.]]
+[[Category: Hsieh P]]
-[[Category: Junop, M S.]]
+[[Category: Junop MS]]
-[[Category: Obmolova, G.]]
+[[Category: Obmolova G]]
-[[Category: Rausch, K.]]
+[[Category: Rausch K]]
-[[Category: Yang, W.]]
+[[Category: Yang W]]
-[[Category: Abc atpase]]
-[[Category: Kinked dna]]
-[[Category: Multi-domain structure]]
-[[Category: Protein-dna complex]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul  1 04:02:12 2008''