7dd3: Difference between revisions

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-'''Unreleased structure'''
-The entry 7dd3 is ON HOLD  until Paper Publication
+==Cryo-EM structure of the pre-mRNA-loaded DEAH-box ATPase/helicase Prp2 in complex with Spp2==
+<StructureSection load='7dd3' size='340' side='right'caption='[[7dd3]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[7dd3]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7DD3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7DD3 FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7dd3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7dd3 OCA], [https://pdbe.org/7dd3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7dd3 RCSB], [https://www.ebi.ac.uk/pdbsum/7dd3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7dd3 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/PRP2_YEAST PRP2_YEAST] Involved in pre-mRNA splicing. Is required together with ATP and at least one other factor, for the first cleavage-ligation reaction. Functions as a molecular motor in the activation of the precatalytic spliceosome for the first transesterification reaction of pre-mRNA splicing by hydrolyzing ATP to cause the activation of the spliceosome without the occurrence of splicing. Capable of hydrolyzing nucleoside triphosphates in the presence of single-stranded RNAs such as poly(U).<ref>PMID:14730020</ref> <ref>PMID:1534753</ref> <ref>PMID:2251118</ref> <ref>PMID:8112302</ref> <ref>PMID:8943336</ref>
-Authors:
+==See Also==
+*[[Helicase 3D structures|Helicase 3D structures]]
-Description:
+*[[Pre-mRNA splicing factors 3D structures|Pre-mRNA splicing factors 3D structures]]
-[[Category: Unreleased Structures]]
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Saccharomyces cerevisiae]]
+[[Category: Bai R]]
+[[Category: Lei J]]
+[[Category: Qi J]]
+[[Category: Shi Y]]
+[[Category: Wan R]]
+[[Category: Yan C]]
+[[Category: Zhang P]]