6t35: Difference between revisions
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==Crystal structure of AmpC from E.coli with Enmetazobactam (AAI-101)== | ==Crystal structure of AmpC from E.coli with Enmetazobactam (AAI-101)== | ||
<StructureSection load='6t35' size='340' side='right'caption='[[6t35]]' scene=''> | <StructureSection load='6t35' size='340' side='right'caption='[[6t35]], [[Resolution|resolution]] 1.75Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6T35 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6T35 FirstGlance]. <br> | <table><tr><td colspan='2'>[[6t35]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6T35 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6T35 FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6t35 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6t35 OCA], [https://pdbe.org/6t35 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6t35 RCSB], [https://www.ebi.ac.uk/pdbsum/6t35 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6t35 ProSAT]</span></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=M9W:Enmetazobactam+derived+trans-enamine+adduct.'>M9W</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6t35 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6t35 OCA], [https://pdbe.org/6t35 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6t35 RCSB], [https://www.ebi.ac.uk/pdbsum/6t35 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6t35 ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/AMPC_ECOLI AMPC_ECOLI] This protein is a serine beta-lactamase with a substrate specificity for cephalosporins. | |||
==See Also== | ==See Also== | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Escherichia coli K-12]] | |||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Brem J]] | [[Category: Brem J]] | ||
Latest revision as of 13:48, 27 March 2024
Crystal structure of AmpC from E.coli with Enmetazobactam (AAI-101)Crystal structure of AmpC from E.coli with Enmetazobactam (AAI-101)
Structural highlights
FunctionAMPC_ECOLI This protein is a serine beta-lactamase with a substrate specificity for cephalosporins. See Also |
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