6j5b: Difference between revisions

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-'''Unreleased structure'''
-The entry 6j5b is ON HOLD
+==Structural basis for the target DNA recognition and binding by the MYB domain of phosphate starvation response regulator 1==
+<StructureSection load='6j5b' size='340' side='right'caption='[[6j5b]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
-Authors: Jiang, M.Q., Sun, L.F., Isupov, M.N., Wu, Y.K.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6j5b]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6J5B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6J5B FirstGlance]. <br>
-Description: Structural basis for the target DNA recognition and binding by the MYB domain of phosphate starvation response regulator 1
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6j5b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6j5b OCA], [https://pdbe.org/6j5b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6j5b RCSB], [https://www.ebi.ac.uk/pdbsum/6j5b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6j5b ProSAT]</span></td></tr>
-[[Category: Wu, Y.K]]
+</table>
-[[Category: Sun, L.F]]
+== Function ==
-[[Category: Jiang, M.Q]]
+[https://www.uniprot.org/uniprot/PHR1_ARATH PHR1_ARATH] Transcription factor involved in phosphate starvation signaling (PubMed:11511543, PubMed:17927693, PubMed:26586833). Binds as a dimer to P1BS, an imperfect palindromic sequence 5'-GNATATNC-3', to promote the expression of inorganic phosphate (Pi) starvation-responsive genes (PubMed:11511543, PubMed:20838596, PubMed:26586833). SPX1 is a competitive inhibitor of this DNA-binding (PubMed:25271326). PHR1 binding to its targets is low Pi-dependent (PubMed:25271326). Regulates the expression of miR399 (PubMed:20838596). Regulates the expression of IPS1 (At3g09922), a non-coding RNA that mimics the target of miR399 to block the cleavage of PHO2 under Pi-deficient conditions (PubMed:17643101). Regulates lipid remodeling and triacylglycerol accumulation during phosphorus starvation (PubMed:25680792). Required for the shoot-specific hypoxic response (PubMed:24753539). Regulates FER1 expression upon phosphate starvation, linking iron and phosphate homeostasis (PubMed:23788639). Contributes to the homeostasis of both sulfate and phosphate in plants under phosphate deficiency (PubMed:21261953). Required for adaptation to high light and retaining functional photosynthesis during phosphate starvation (PubMed:21910737). Involved in the coregulation of Zn and Pi homeostasis (PubMed:24420568).<ref>PMID:11511543</ref> <ref>PMID:17643101</ref> <ref>PMID:17927693</ref> <ref>PMID:20838596</ref> <ref>PMID:21261953</ref> <ref>PMID:21910737</ref> <ref>PMID:23788639</ref> <ref>PMID:24420568</ref> <ref>PMID:24753539</ref> <ref>PMID:25271326</ref> <ref>PMID:25680792</ref> <ref>PMID:26586833</ref>
-[[Category: Isupov, M.N]]
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Arabidopsis thaliana]]
+[[Category: Large Structures]]
+[[Category: Synthetic construct]]
+[[Category: Isupov MN]]
+[[Category: Jiang MQ]]
+[[Category: Sun LF]]
+[[Category: Wu YK]]