6iy3: Difference between revisions
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==Structure of Snf2-MMTV-A nucleosome complex at shl-2 in ADP state== | |||
<SX load='6iy3' size='340' side='right' viewer='molstar' caption='[[6iy3]], [[Resolution|resolution]] 3.67Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6iy3]] is a 11 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus], [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C] and [https://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IY3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6IY3 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.67Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6iy3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6iy3 OCA], [https://pdbe.org/6iy3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6iy3 RCSB], [https://www.ebi.ac.uk/pdbsum/6iy3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6iy3 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/H4_XENLA H4_XENLA] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | |||
==See Also== | |||
*[[Helicase 3D structures|Helicase 3D structures]] | |||
*[[Histone 3D structures|Histone 3D structures]] | |||
[[Category: | __TOC__ | ||
[[Category: | </SX> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Mus musculus]] | ||
[[Category: Chen | [[Category: Saccharomyces cerevisiae S288C]] | ||
[[Category: Li | [[Category: Xenopus laevis]] | ||
[[Category: Chen Z]] | |||
[[Category: Li M]] | |||
[[Category: Li X]] | |||
[[Category: Liu X]] | |||
[[Category: Xia X]] | |||
Latest revision as of 13:35, 27 March 2024
Structure of Snf2-MMTV-A nucleosome complex at shl-2 in ADP stateStructure of Snf2-MMTV-A nucleosome complex at shl-2 in ADP state
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