6iro: Difference between revisions

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OCA

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-'''Unreleased structure'''
-The entry 6iro is ON HOLD
+==the crosslinked complex of ISWI-nucleosome in the ADP-bound state==
+<SX load='6iro' size='340' side='right' viewer='molstar' caption='[[6iro]], [[Resolution|resolution]] 3.40&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6iro]] is a 11 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12], [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C] and [https://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IRO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6IRO FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.4&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6iro FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6iro OCA], [https://pdbe.org/6iro PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6iro RCSB], [https://www.ebi.ac.uk/pdbsum/6iro PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6iro ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/H4_XENLA H4_XENLA] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
-Authors: Yan, L.J., Wu, H., Li, X.M., Gao, N., Chen, Z.C.
+==See Also==
+*[[Histone 3D structures|Histone 3D structures]]
-Description: the crosslinked complex of ISWI-nucleosome in the ADP-bound state
+__TOC__
-[[Category: Unreleased Structures]]
+</SX>
-[[Category: Li, X.M]]
+[[Category: Escherichia coli K-12]]
-[[Category: Chen, Z.C]]
+[[Category: Large Structures]]
-[[Category: Gao, N]]
+[[Category: Saccharomyces cerevisiae S288C]]
-[[Category: Yan, L.J]]
+[[Category: Xenopus laevis]]
-[[Category: Wu, H]]
+[[Category: Chen ZC]]
+[[Category: Gao N]]
+[[Category: Li XM]]
+[[Category: Wu H]]
+[[Category: Yan LJ]]