6a1v: Difference between revisions

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'''Unreleased structure'''


The entry 6a1v is ON HOLD  until Paper Publication
==Charcot-Leyden crystal protein/Galectin-10 variant E33Q==
<StructureSection load='6a1v' size='340' side='right'caption='[[6a1v]], [[Resolution|resolution]] 1.98&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6a1v]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6A1V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6A1V FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.984&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6a1v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6a1v OCA], [https://pdbe.org/6a1v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6a1v RCSB], [https://www.ebi.ac.uk/pdbsum/6a1v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6a1v ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/LEG10_HUMAN LEG10_HUMAN] Regulates immune responses through the recognition of cell-surface glycans. Essential for the anergy and suppressive function of CD25-positive regulatory T-cells (Treg).<ref>PMID:17502455</ref>


Authors: Su, J.Y.
==See Also==
 
*[[Galectin 3D structures|Galectin 3D structures]]
Description: Charcot-Leyden crystal protein/Galectin-10 variant E33Q
== References ==
[[Category: Unreleased Structures]]
<references/>
[[Category: Su, J.Y]]
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Su J]]

Latest revision as of 13:30, 27 March 2024

Charcot-Leyden crystal protein/Galectin-10 variant E33QCharcot-Leyden crystal protein/Galectin-10 variant E33Q

Structural highlights

6a1v is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.984Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

LEG10_HUMAN Regulates immune responses through the recognition of cell-surface glycans. Essential for the anergy and suppressive function of CD25-positive regulatory T-cells (Treg).[1]

See Also

References

  1. ↑ Kubach J, Lutter P, Bopp T, Stoll S, Becker C, Huter E, Richter C, Weingarten P, Warger T, Knop J, Mullner S, Wijdenes J, Schild H, Schmitt E, Jonuleit H. Human CD4+CD25+ regulatory T cells: proteome analysis identifies galectin-10 as a novel marker essential for their anergy and suppressive function. Blood. 2007 Sep 1;110(5):1550-8. doi: 10.1182/blood-2007-01-069229. Epub 2007 May, 14. PMID:17502455 doi:http://dx.doi.org/10.1182/blood-2007-01-069229

6a1v, resolution 1.98Å

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