6a1u: Difference between revisions

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'''Unreleased structure'''


The entry 6a1u is ON HOLD  until Paper Publication
==Charcot-Leyden crystal protein/Galectin-10 variant E33D==
<StructureSection load='6a1u' size='340' side='right'caption='[[6a1u]], [[Resolution|resolution]] 1.62&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6a1u]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6A1U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6A1U FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.62&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6a1u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6a1u OCA], [https://pdbe.org/6a1u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6a1u RCSB], [https://www.ebi.ac.uk/pdbsum/6a1u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6a1u ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/LEG10_HUMAN LEG10_HUMAN] Regulates immune responses through the recognition of cell-surface glycans. Essential for the anergy and suppressive function of CD25-positive regulatory T-cells (Treg).<ref>PMID:17502455</ref>


Authors: Su, J.Y.
==See Also==
 
*[[Galectin 3D structures|Galectin 3D structures]]
Description: Charcot-Leyden crystal protein/Galectin-10 variant E33D
== References ==
[[Category: Unreleased Structures]]
<references/>
[[Category: Su, J.Y]]
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Su J]]

Latest revision as of 13:30, 27 March 2024

Charcot-Leyden crystal protein/Galectin-10 variant E33DCharcot-Leyden crystal protein/Galectin-10 variant E33D

Structural highlights

6a1u is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.62Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

LEG10_HUMAN Regulates immune responses through the recognition of cell-surface glycans. Essential for the anergy and suppressive function of CD25-positive regulatory T-cells (Treg).[1]

See Also

References

  1. ↑ Kubach J, Lutter P, Bopp T, Stoll S, Becker C, Huter E, Richter C, Weingarten P, Warger T, Knop J, Mullner S, Wijdenes J, Schild H, Schmitt E, Jonuleit H. Human CD4+CD25+ regulatory T cells: proteome analysis identifies galectin-10 as a novel marker essential for their anergy and suppressive function. Blood. 2007 Sep 1;110(5):1550-8. doi: 10.1182/blood-2007-01-069229. Epub 2007 May, 14. PMID:17502455 doi:http://dx.doi.org/10.1182/blood-2007-01-069229

6a1u, resolution 1.62Å

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