5z8s: Difference between revisions

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'''Unreleased structure'''


The entry 5z8s is ON HOLD  until Paper Publication
==Human Mitochondrial ferritin mutant - C102A/C130A/E27C/E61C/E62C==
<StructureSection load='5z8s' size='340' side='right'caption='[[5z8s]], [[Resolution|resolution]] 1.97&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5z8s]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Z8S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5Z8S FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.973&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AU:GOLD+ION'>AU</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5z8s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5z8s OCA], [https://pdbe.org/5z8s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5z8s RCSB], [https://www.ebi.ac.uk/pdbsum/5z8s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5z8s ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/FTMT_HUMAN FTMT_HUMAN] Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.<ref>PMID:11323407</ref> <ref>PMID:15201052</ref>


Authors: Zang, J., Zheng, B., Zhao, G.
==See Also==
 
*[[Ferritin 3D structures|Ferritin 3D structures]]
Description: Human Mitochondrial ferritin mutant -C102A/C130A/E27C/E61C/E62C
== References ==
[[Category: Unreleased Structures]]
<references/>
[[Category: Zhao, G]]
__TOC__
[[Category: Zheng, B]]
</StructureSection>
[[Category: Zang, J]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Zang J]]
[[Category: Zhao G]]
[[Category: Zheng B]]

Latest revision as of 13:27, 27 March 2024

Human Mitochondrial ferritin mutant - C102A/C130A/E27C/E61C/E62CHuman Mitochondrial ferritin mutant - C102A/C130A/E27C/E61C/E62C

Structural highlights

5z8s is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.973Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

FTMT_HUMAN Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.[1] [2]

See Also

References

  1. ↑ Levi S, Corsi B, Bosisio M, Invernizzi R, Volz A, Sanford D, Arosio P, Drysdale J. A human mitochondrial ferritin encoded by an intronless gene. J Biol Chem. 2001 Jul 6;276(27):24437-40. Epub 2001 Apr 25. PMID:11323407 doi:http://dx.doi.org/10.1074/jbc.C100141200
  2. ↑ Langlois d'Estaintot B, Santambrogio P, Granier T, Gallois B, Chevalier JM, Precigoux G, Levi S, Arosio P. Crystal structure and biochemical properties of the human mitochondrial ferritin and its mutant Ser144Ala. J Mol Biol. 2004 Jul 2;340(2):277-93. PMID:15201052 doi:10.1016/j.jmb.2004.04.036

5z8s, resolution 1.97Å

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