5z3u: Difference between revisions
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==Structure of Snf2-nucleosome complex at shl2 in ADP BeFx state== | |||
<SX load='5z3u' size='340' side='right' viewer='molstar' caption='[[5z3u]], [[Resolution|resolution]] 4.31Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5z3u]] is a 11 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C], [https://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Z3U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5Z3U FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.31Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=BEF:BERYLLIUM+TRIFLUORIDE+ION'>BEF</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5z3u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5z3u OCA], [https://pdbe.org/5z3u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5z3u RCSB], [https://www.ebi.ac.uk/pdbsum/5z3u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5z3u ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/SNF2_YEAST SNF2_YEAST] Involved in transcriptional activation. Catalytic component of the SWI/SNF complex, an ATP-dependent chromatin-remodeling complex, which is required for the positive and negative regulation of gene expression of a large number of genes. It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors. | |||
==See Also== | |||
*[[Helicase 3D structures|Helicase 3D structures]] | |||
*[[Histone 3D structures|Histone 3D structures]] | |||
[[Category: | __TOC__ | ||
[[Category: | </SX> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Chen | [[Category: Saccharomyces cerevisiae S288C]] | ||
[[Category: Li | [[Category: Synthetic construct]] | ||
[[Category: Li | [[Category: Xenopus laevis]] | ||
[[Category: Chen Z]] | |||
[[Category: Li M]] | |||
[[Category: Li X]] | |||
[[Category: Liu X]] | |||
[[Category: Xia X]] |